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Showing 1 to 1 of 1 for “"targeted endogenous integration"”.

  1. Natural and Exogenous Genome Editing In Wiskott-Aldrich Syndrome Patient Cells

    … Subsequently, a WAS-2A-eGFP transgene was targeted at the endogenous chromosomal location by homology-directed repair using ZFN, thereby correcting the gene defect and creating a GFP reporter for WASp expression. Hematopoietic progenitor cells were generated from WAS iPSC and gene-corrected …

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