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Showing 1 to 1 of 1 for “"tangle formation"”.

  1. Apolipoprotein E and propagation of pathological tau in Alzheimer’s Disease

    … and hyperphosphorylated tau in neurofibrillary tangles. This occurs alongside neuroinflammation and neurodegeneration. Clinically, AD is typified by cognitive decline. Pathological tau propagates through the AD brain in a defined manner, with indications this occurs trans-synaptically. Spread of …

    edinburgh Repository record for Apolipoprotein E and propagation of pathological tau in Alzheimer’s Disease (opens in a new tab)