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Showing 1 to 2 of 2 for “"tacrines"”.

  1. Mild and Convenient Methods to Prepare N-Alkyl Tacrines

    … treatment of AD. Synthesis of various bivalent tacrines led to the improvement in inhibitory potency and selectivity towards inhibition of AChE. Heptylene-linked bis-tacrine has especially shown immense promise to be an ideal AChEI. Thus dimerization of a lead compound seemed to be an ideal …

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  2. Toxicological Analysis of Tacrines and Verapamil on the Yellow Fever Mosquito, Aedes aegypti

    Mosquitoes affect human health worldwide as a result of their ability to vector multiple diseases. Mosquitocide resistance is a serious public health challenge that warrants the development of improved chemical control strategies for mosquitoes. Previous studies demonstrate the mosquito blood-brain …

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