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Showing 1 to 2 of 2 for “"tacrine dimers"”.

  1. Experimental and Computational Investigation of Tacrine-Based Inhibitors of Acetylcholinesterase

    … loss was 9-amino-1,2,3,4-tetrahydroacridine (tacrine). Inhibition of AChE may present either therapeutic or toxic effects depending upon the dose administered. With the goal of discovering safe and effective pesticides to control the population of Anopheles gambiae, a malaria-transmitting …

    vt Repository record for Experimental and Computational Investigation of Tacrine-Based Inhibitors of Acetylcholinesterase (opens in a new tab)

  2. Molecular, Biochemical, and Toxicological Evaluation of Anticholinesterases for control of the Malaria Mosquito, Anopheles gambiae

    Pyrethroids are the only class of insecticides approved by the World Health Organization (WHO) for use in insecticide treated nets (ITNs), the first line of malaria vector control. Widespread resistance development to pyrethroids undermines current control efforts, and hence an urgent need for …

    vt Repository record for Molecular, Biochemical, and Toxicological Evaluation of Anticholinesterases for control of the Malaria Mosquito, Anopheles gambiae (opens in a new tab)