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Showing 1 to 5 of 5 for “"tRNA Ligase"”.
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Investigations of peptide aminoacyl tRNA ligase (PEARL) biosynthetic gene clusters
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Mechanismus des pre-tRNA-Spleißens : Struktur und Funktion pflanzlicher und animaler RNA-Ligasen
… werden von der RNA Polymerase III als Vorläufer tRNA transkribiert und durchlaufen eine Vielzahl von Reifungsschritten hin zur maturen tRNA. Neben der Hydrolyse der 5´- und 3´-Flanke durch die RNase P und die tRNase Z, sowie einer Vielzahl von Basenmodifizierungen, wird bei einigen pre-tRNAs das …
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Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases
<p>Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases</p> <p>Khondakar Sayef Ahammed, M.S.</p> <p>Advisory Professor: Ambro van Hoof, Ph.D.</p> <p><strong> </strong></p> <p>RNA maturation and degradation reactions are important for health and survival of all …
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Characterizing peptide-modifying enzyme activity in RiPP biosynthesis
… was made towards the study of aminoacyl-tRNA specificity in a peptide aminoacyl-tRNA ligase (PEARL) enzyme. Using flexizyme-generated aminoacyl-tRNAs, both the amino acid and tRNA body were shown to jointly encode specificity while still permitting incorporation of noncanonical amino, …
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Characterization of Amino Acid tRNA Ligases using the Analytical Ultracentrifuge
ABSTRACT. Quaternary structures of amino acid tRNA ligases/synthetases (aaRS) in the native as well as in denatured forms were examined by molecular weight determinations (paper I-IV). Analytical ultracentrifugation, gel electrophoresis, gel chromatography were used in these investigations. The …