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Showing 1 to 1 of 1 for “"tRNA (m1G37) methyltransferase"”.

  1. Inhibition of enzymes from mycobacteria using fragment-based approaches

    Whitehouse, Andrew JohnUniversity of Cambridge2019

    … from Mycobacterium tuberculosis (Mtb) and tRNA (m1G37) methyltransferase (TrmD) from Mycobacterium abscessus (Mab). With Mtb fumarase a high-throughput screening (HTS) hit was used to design a small library of fragments in a deconstruction-reconstruction approach. These fragments were …

    cambridge Repository record