Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"t-cell maturation"”.
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The Role of Map Kinases On The Functional Heterogeneity of Human Cd8+ T Cell Maturation Subsets
… and early stage memory (CD45RA-CD27+) CD8+ T cells, late memory CD8+ T cells (CD45RA+CD27) have received less interest because this subset of T cells is generally recognized as effectors, which produce IFNγ (but no IL-2) and perforin. However, multiple studies suggest that late memory CD8+ T …
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Analysis of DIE5 and LIA5 reveals the importance of DNA repair in programmed DNA rearrangement of Tetrahymena thermophila
… its somatic nuclear differentiation, the single cell eukaryote Tetrahymena thermophila undergoes genome-wide programmed DNA rearrangement to eliminate transposon-like elements from its future soma. This process involves small RNA-directed heterochromatin formation followed by extensive nuclear …
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Regulation of Autoimmunity and Inflammation by microRNAs and Environmental Factors
… and have been described to have defects in the T cell maturation. By studying the apoptosis response of NOD lymphocytes (which activates similar cell-cycle checkpoints and apoptosis pathways as during thymocyte maturation) we showed differential expression of the miRNA-34a/b/c gene family, miR-125 …
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Rare event simulation for probabilistic models of T-cell activation
… is critical for our survival. One of the major cell types involved in these decisions are the so called T-cells, which are specialized white blood cells with a detection mechanism that is not fully explained until now. There is not a one to one specificity between T-cells and antigens. T-cells …
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Abnormes Mikromilieu und gestörte Thymopoese in Thymomen als Grundlage der Autoimmunisierung im peripheren Immunsystem
… growth-associated molecule" (HB-GAM) und der "B-cell growth factor 1" (BCGF 1) hervorzuheben. Die Expression von HB-GAM zeigte sowohl eine Abhängigkeit vom histologischen Thymomtyp (kortikal > gemischt / medullär) als auch vom MG-Status der Patienten (MG+ > MG-).Umgekehrt wurde für den Faktor …
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Aspects of the Immunobiology of Myelin Oligodendrocyte Glycoprotein (MOG)-induced Experimental Autoimmune Encephalomyelitis (EAE)
… the different kinetics of MOG-specific T and B cell responses. In MS we still have to answer two crucial questions, namely the identity of the autoantigens targeted by the demyelinating antibody response, and the factors that may trigger this response. MOG is the only myelin protein known to …