Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 143 for “"systemic lupus erythematosus"”.
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Spirituality And Systemic Lupus Erythematosus
… in a sample of individuals diagnosed with Systemic Lupus Erythematosus (SLE). Furthermore, relational spirituality has yet to be studied in a chronically ill population. Meeting these gaps in the literature, this study compared the explicit domains and latent constructs measured by a …
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Studies of Atherosclerosis in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the production of anti-nuclear autoantibodies, a wide spectrum of clinical signs, and a striking 9:1 female to male disparity in disease incidence attributed to the SLE disease promoting effects of estrogen. …
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Selective HDAC6 Inhibition in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by abnormalities in multiple components of the immune system resulting in progressive damage to multiple organs. Current treatments for SLE are often intensive and result in side effects and the potential for …
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Phagocytosis of apoptotic cells and systemic lupus erythematosus
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The Effects of Pregnancy on Systemic Lupus Erythematosus
<p>The safety of pregancy for the woman with systemic lupus erythematosus (SLE) has long been studied. Controversy exists about the occurrence of exacerbations during pregnancy and the effect these exacerbations will have on the basic disease process. The purpose of this study was to investigate …
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Immune memory and activation markers in systemic lupus erythematosus
Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by the loss of tolerance to self-antigens, immune complex deposition, tissue inflammation and destruction. SLE manifestations, prevalence and severity vary among different populations and ethnicities. Even …
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Genetic Polymorphisms of Interleukin-6 in Systemic Lupus Erythematosus
BACKGROUNDS: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by polyclonal B-cell activation and elevated production of pathogenic autoantibodies. Interleukin-6 (IL-6) is a multifunctional cytokine that mediates inflammatory and immune responses, and IL-6 gene …
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Specificity of Anti-Dna Antibodies in Systemic Lupus Erythematosus
… of anti-DNA antibodies in the disease systemic lupus erythematosus (SLE), the specificity of naturally occuring anti-DNA antibody in plasma of human patients with SLE was studied in detail.
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Does alopecia have diagnostic weight in systemic lupus erythematosus?
Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterised by autoantibody production and a wide spectrum of clinical manifestations. Non-scarring alopecia (hair loss) is reported to occur in up to 80% of individuals with SLE, occurring primarily in the active phase. …
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The role of gut microbiota in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease with no known cure. Despite years of study, the etiology of SLE is still unclear. Both genetic and environmental factors have been implicated in the disease mechanisms. Gut microbiota as an environmental factor and the immune …
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Identification of microRNA associated with systemic lupus erythematosus in Korean
BACKGROUNDS: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by polyclonal B-cell activation and elevated production of pathogenic autoantibodies. MicroRNAs (miRNAs) are short, noncoding RNAs that regulate gene expression on the post translational level, which can be …
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Significance of vitamin D in systemic lupus erythematosus in Koreans
… 측정하였다. 루푸스 환자에서 채혈 당시의 임상 양상과 검사실 검사 결과를 확인하여 systemic lupus erythematosus disease activity index (SLEDAI)와 systemic lupus international collaborative clinics/american college of rheumatology damage index (SLICC/ACR DI)를 평가하였다. 또한 루푸스 환자에서 항염색질 항체를 면역효소법을 이용하여 측정하였다. 결과: 혈청 25(OH)D은 전신성 홍반성 루푸스 …
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Significance of leptin and ghrelin in systemic lupus erythematosus in Koreans
… levels have been described in patients with systemic lupus erythematosus (SLE), however there were no information about serum leptin and ghrelin level, antagonist hormone of leptin, in patients with SLE. We have evaluated the differences of serum leptin and ghrelin levels between patients …
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Treatment of Systemic Lupus Erythematosus by Nutrition and Dendritic Cell Targeting
Systemic lupus erythematosus (SLE) is an autoimmune disease involving the inflammatory damages of multiple organs. Lupus nephritis (LN) as the manifestation in the kidney occurs in more than 50% of SLE patients and is a major cause of morbidity and mortality. Current treatments consist of …
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The Role of Histone Deacetylase 6 Inhibition on Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic multifactorial inflammatory autoimmune disease with heterogeneous clinical manifestations. Among different manifestations, lupus nephritis (LN) remains a major cause of morbidity and mortality. There are few FDA approved treatments for LN. In general, …
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Pathogenic and Protective Potential of B Cell Dysregulation in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of tolerance to nuclear antigens. Hyperactive B cells are present in SLE patients and murine models of lupus, many of which have defects in inhibitors of B cell receptor (BCR) signaling or plasma cell differentiation. …
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Cardiovascular risk factors and carotid intima-media thickness in systemic lupus erythematosus
목적 : 전신성 홍반성 루푸스(이하 루푸스)는 주로 가임기의 젊은 여성에게 많이 나타나는 자가면역 질환으로 정상인에 비해 조기에 죽상경화증이 발생하며 이는 루푸스 환자 사망의 중요한 원인이라고 알려져 있다. 이에 심혈관계 질환이 없는 루푸스 환자에서 죽상경화의 진행을 보여주는 경동맥 내막-중막 두께와 경동맥 플라크를 측정하여 정상인과 비교해보고 루푸스 질병 활성도를 나타내는 인자와의 관련성을 알아보고자 한다. 재료 및 방법 : 아주대학교 병원 류마티스 내과에서 미국 류마티스 학회에서 1982년 개정한 루푸스 진단 기준에 맞는 여성 …
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Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
… for the study on the basis of 1: A diagnosis of systemic Lupus Erythematosus according to the 1982 revised American Rheumatology Association criteria47 and 2: An adequate biopsy defined as containing at least six glomeruli. Patients were biopsied at Groote Schuur Hospital during the period 1978 …
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