Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"systemic inflammatory response syndrome"”.
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Glucocorticoid Receptor Density and Binding Affinity in Horses with Systemic Inflammatory Response Syndrome
… the HPA axis in adult horses presenting with systemic inflammatory response syndrome (SIRS), and to determine where any alterations in HPA axis function occur in these patients compared to healthy adults. For the first part of the study, peripheral venous blood was collected from 3 healthy …
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Chemokines as therapeutic targets in systematic inflammatory response syndrome
Exaggerated systemic inflammatory response syndrome may lead to multiple organ dysfunction, organ failure and eventually death. Chemokines, a large family of small chemotactic cytokines, are critical inflammatory mediators in the development of both acute pancreatitis and sepsis. The present study …
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Early Identification of Sepsis in the Walk-in Setting
Sepsis is the body’s dysregulated response to infection and is the cause of significant physical and financial burden on patients and the healthcare system. If not identified and treated promptly, sepsis can result in high rates of morbidity and mortality. Prehospital settings, such as walk-in …
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Improving Early Sepsis Identification on Inpatient Units
… which is initiated by the body’s extreme response to an infection. If sepsis is not identified and treated promptly, it can rapidly lead to tissue damage, organ failure and death. In order to reduce the number of patients who decline to sepsis in hospital, an efficient sepsis protocol …
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Rapid pre-symptomatic diagnosis of sepsis by vibrational spectroscopy
Sepsis is a dysregulated host response to an infection that causes life-threatening organ dysfunction. Each year, over 30 million cases and 5 million deaths are estimated worldwide. Diagnosis of sepsis is based on non-specific clinical signs and time consuming positive identification of the …
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CLINICAL APPLICATIONS OF PARAOXONASE-1 IN DOMESTIC ANIMALS: BEYOND CONVENTIONAL INFLAMMATORY MARKERS
… animals. The diagnosis and monitoring of inflammatory and oxidative conditions are based on markers that are so far considered accurate but may lack specificity and prognostic utility. In the last years’ research, interest has grown about the role of Paraoxonase-1 (PON-1) in the …
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Aspects of sepsis/SIRS - An experimental study on fluid therapy, vitamin C and plasma volume in increased permeability
… various degrees of generalized inflammation, a syndrome called Systemic Inflammatory Response Syndrome (SIRS). One feature of SIRS is increased capillary permeability, caused by disruption of the capillary endothelium due to e.g. bacterial toxins, cytokines, pro-inflammatory hormones and free …
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Rac1 signaling regulates platelet-dependent inflammation abdominal sepsis
Sepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced …
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Improving Early Sepsis Identification
… which is initiated by the body’s extreme response to an infection. If sepsis is not identified and treated promptly, it can rapidly lead to tissue damage, organ failure and death. Accounting for high morbidity and mortality rates in the United States, sepsis has become an area of focus …
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Connective Tissue Growth Factor in Pancreatitis
Pancreatitis is an inflammatory condition of the pancreas in which pancreatic acinar cells (PAC) become injured by noxious agents and produce pro-inflammatory mediators. Excessive alcohol consumption is a major cause of pancreatitis in the West. Acute pancreatitis (AP) can be recurrent and severe, …
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Immune biomarkers predicting clinical outcomes for major trauma patients
… in the UK, sepsis and multiple organ dysfunction syndrome (MODS) continue to be severe complications of trauma worldwide. Ongoing research exploring the immune response to trauma over the years has highlighted the systemic inflammatory response syndrome (SIRS) as an early immune response to …
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Transcriptomic predictors of outcomes in acute infection
… organ dysfunction due to a dysregulated host response to infection, lead to high patient morbidity and mortality. Conditions that mimic acute infections and sepsis also lead to delays in appropriate patient care and adverse outcomes given the low threshold for suspicion and initial treatment …
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Phänotypische und funktionelle Charakterisierung lymphozytärer Subpopulationen nach ausgedehnter Verbrennungsverletzung
… daher hochgradig gefährdet ein ausgedehntes „systemic inflammatory response syndrome, (SIRS)“, d. h. eine maligne Ganzkörperinflammation, eine Sepsis oder eine Multiorgandysfunktion, assoziiert mit einer hohen Letalität, zu entwickeln. Eine überwiegend antiinflammatorische Immunantwort dagegen …
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An investigation of liver blood flow in systemic inflammation
Inflammatory stimuli such as infection or tissue injury will produce a local inflammatory response which may, if the inflammatory response is sufficiently large, spill over to produce a systemic inflammatory response. This is clinically characterized by a response in heart and respiratory rate, a …