Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 152 for “"systemic inflammation"”.
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An investigation of liver blood flow in systemic inflammation
… is sufficiently large, spill over to produce a systemic inflammatory response. This is clinically characterized by a response in heart and respiratory rate, a temperature rise or fall and a white cell response. Where the systemic inflammatory response syndrome is due to proven infection this is …
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Role of adipose tissue as an endocrineorgan in systemic inflammation
… disorders are characterised by mild chronic inflammation as a result of adipocytokine production from fat tissue leading to dysregulation in the pro/anti‐inflammatory systemic balance. Adipokines and pro‐inflammatory markers are implicated in insulin insensitivity, blood glucose …
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Developing brain and systemic inflammation: a "Toll-like" link with consequences
… available. Hypoxia/ischemia (HI), infections and inflammation are implicated in the pathogenesis of PBI. However, the crosstalk between these etiologies is not fully understood. Toll-like receptors (TLR) 3 and TLR2 are responsible for sensing viral and bacterial infections and initiating the …
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Risk of depression and cardiovascular disease across the lifespan: the role of systemic inflammation.
… shared pathophysiological mechanisms, such as systemic inflammation, may be involved. However, the direction of association between depression and CVD risk in young people remains unclear. Gaps also remain in our understanding of the role of different immune components in these relationships …
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The role of systemic inflammation and the apolipoprotein E gene in human immunodeficiency virus-associated cognitive impairment
Includes abstract. Includes bibliographical references.
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Lymphatic Dysfunction and Associated Systemic Inflammation In Lymphedema, Assessed By Nirf-Li Imaging and Plasma Cytokine/Chemokine Analysis
… conclusion, these studies show that 1) BCRL is a systemic, persistently inflammatory, disease, 2) NIRF-LI is a better tool for BCRL surveillance than perometric arm volume measurement and 3) reparative microsurgeries for BCRL need further study.</p>
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ASPECTS OF FLUID THERAPY: An experimental study of the effects of systemic inflammation, microvascular permeability, blood pressure and plasma volume
… be influenced by such physiological factors as systemic inflammation, microvascular permeability, blood pressure, and prevailing plasma volume. This doctoral thesis based on 5 experimental studies performed on the rat and on the guinea pig, is aimed at evaluating the plasma volume expanding …
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Serum Osteoprotegerin, a Potential Novel Marker of Systemic Inflammation: The Influence of Obesity, Insulin Sensitivity and Oral Glucose Loading on its Circulating Concentrations
… secretion, insulin resistance, adiposity or systemic inflammation is the main regulatory factor.
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Plasticity of Adrenal Chromaffin Cell Function During Inflammation and Exposure to Microbe-Associated Molecular Patterns
… The SNS provides negative feedback control over inflammation through the secretion of catecholamines from postganglionic sympathetic neurons and adrenal chromaffin cells (ACCs). Central autonomic structures receive information regarding the inflammatory status of the body and reflexively modulate …
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Prognostické a prediktivní markery v léčbě karcinomu pankreatu
… Prognostic parameters based on the presence of systemic inflammation have a significant role in many cancers. Inflammation is known to promote tumor progression, leading to shortened survival. In pancreatic cancer, systemic inflammation is common and contributes to its unfavorable prognosis. The …
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Isoprenylation and NET formation in acute pancreatitis
Acute Pancreatitis (AP) is an inflammation disease that characterized by activation of protease and the innate immune system, leading to infiltration of neutrophils and tissue damage in the pancreas. The aim of this thesis was to determine the role of isoprenylation (farnesyltransferase and …
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Role of Cerebral Vasculature and Effect of Circulating Exosomes in Propagation of Systemic Inflammatory Responses into the Central Nervous System
… acutely progressing brain dysfunction induced by systemic inflammation. The mechanism of initiation of neuroinflammation during SAE, which ultimately leads to delirium and cognitive dysfunction, remains elusive. The goal of this project was to study the molecular events of SAE to capture its onset …
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Aquaporin-4 mediates blood brain barrier permeability during endotoxemia
… AQP4 may mediate permeability of the CNS during systemic inflammation. Here, mice were i.v. injected with fluorescent tracers of low (1 kd) and intermediate (10 kd) molecular weights 24 hours after induction of endotoxemia with i.p. LPS. Fluorescent microscopy using tissue sections and cleared …
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AN EXAMINATION OF THE GUT MICROBIOME IN PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDER VERSUS HEALTHY CONTROLS
… in psychiatric conditions. Further, the role of inflammation is also gaining traction in psychiatric research. This thesis investigates the role of these commensal gut bacteria in OCD, by examining stool samples of unmedicated, non-depressed OCD outpatients and healthy community controls. Given …
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Persistent (>6 months) Neuropsychiatric symptoms in a cohort of SARS- CoV-2 PCR positive patients in Cape Town, South Africa
… outcomes with clinical illness severity, systemic inflammation, cardiovascular and renin-angiotensin system (RAS) biomarkers. Methodology: SARS-CoV-2 PCR positive patients were recruited prospectively from Cape Town, South Africa, including hospitalized patients from ancestral, beta and …
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HIGH SENSITIVITY C-REACTIVE PROTEIN AND RISK OF STROKE IN ATRIAL FIBRILLATION: THE REASONS FOR GEOGRAPHIC AND RACIAL DIFFERENCES IN STROKE (REGARDS) STUDY
… C-reactive protein (hs-CRP), a marker of systemic inflammation, is a predictor of cardiovascular events in the general population. We compared the association between hs-CRP level and subsequent stroke events in in individuals with and without atrial fibrillation (AF) in the REGARDS study.
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Understanding periodontal diseases and diabetes through resolvins
… and have been associated with many different systemic diseases such as type 2 diabetes mellitus. Resolvins are a recently discovered set of pro-resolving molecules shown to influence inflammation in both periodontitis and type 2 diabetes mellitus. Published Studies: Periodontitis and type 2 …
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