Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"synthetic polymer"”.
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Synthetic polymer-collagen composite hydrogel for drug delivery and tissue engineering
… and thermo reversible PEO-PPO-PEO tri-block copolymer to achieve composite hydrogel that combined the appropriate mechanical properties of synthetic component with the biocompatibility of biological component. The hydrogel was characterized ultrastructurally and evaluated as a drug carrier by …
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Hybrid Gene Therapy Vectors Comprised of Synthetic Polymer and Noninfectious Virus -Like Particles
… combined some of the beneficial traits of the polymer and viral components the efficiency of the vector is low, in comparison to conventional viral vectors. Based on the changes in gene expression over time and the effect of chloroquine, the limiting step of hybrid vector cell transduction …
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The confined self-assembly of photonic pigments: from synthetic polymer brushes to sustainable cellulosic colloids
… The second system exploits bottlebrush block copolymers (BBCPs). These rigid, giant macromolecules are well-known for microphase separation into a wide variety of nanostructures. Although more challenging to synthesise, BBCPs allow for a very rapid self-assembly process. All previous studies …
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Stabilization of Soft Clay Subgrades in Virginia Phase I Laboratory Study
… Alternatives, including lignosulfonates and polymers, are available, but their performance record is mixed and solid engineering data is lacking, which prevents reliable design. The goal of this research was to screen a suite of traditional and non-traditional stabilizers against three …
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Driving forces of self-assembly in protein-polymer bioconjugates
Protein-polymer bioconjugates have shown great promise as high-performance biomaterials, with a diverse range of applications. Bioconjugation to a polymer allows the protein to maintain or even enhance its activity while imparting self-assembly capabilities to the overall material, which provide …
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Polymer Gradient Materials
… preparation and characterization of longitudinal polymer gradient materials (PGMs). The inspiration for this work comes from nature: mussel byssus threads are soft-hard gradient biomaterials. These gradient threads are formed by a polyaddition process, show unique mechanical properties and …
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PREPARATION AND CHARACTERIZATION OF AN ELECTROSPUN GELATIN/DENDRIMER HYBRID NANOFIBER DRESSING
… chronic wounds. Comprised of gelatin, dendrimer, synthetic polymer and antibiotics, the dressing was electrospun to mimic the natural extracellular matrix (ECM). Gelatin is biocompatible, biodegradable, non-toxic, and easily available. The antibiotic, doxycycline, has the ability to inhibit matrix …
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Electrospun Scaffolds for Cartilage Tissue Engineering: Methods to Affect Anisotropy, Material and Cellular Infiltration
… which was electrospun as a composite with a synthetic polymer. This work provided advances in three major areas of tissue engineering: scaffold properties, cell-scaffold interaction, and novel materials.</p>
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Polymer-tethered epidermal growth factor as an inductive biomaterial surface for connective tissue progenitors
… project entails the design of a two-component polymeric implant system to aid in the healing process of bony defects by influencing cell behaviors at the implant site through the covalent modification of the implant surface with selected ligands. We investigate cellular responses of CTP on a …
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Thermal and morphological analysis of collagen-plla electrospun blends
… blended nanofibers of a protein, collagen, and a synthetic polymer, poly (L-lactic acid). This study focuses on the in-depth analysis of the appearance of the structural relaxation occurring at the glass transition temperature of PLLA in the collagen-PLLA blended electrospun mats. It is speculated …
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Decellularized cartilage as a chondroinductive material for cartilage tissue engineering
… tissue engineering scaffolds have utilized synthetic polymer components to form hydrogels or other porous matrices. However, components found within the extracellular matrix (ECM) such as collagen, glycosaminoglycans (GAGs), and ECM-based matrices have emerged as an essential subset of …
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Aspects of ultrasonic relaxation spectrometry
… alkyl sulphates and N-polyvinylpyrrolidone, a synthetic polymer, in aqueous solution at detergent concentrations above and below the surfactant critical micelle concentration.Finally, counterion-polyion binding has been studied insolutions of a number of polyelectrolytes including a range of …
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A Bio-Inspired Self-Healing Polymer System for Sustainable Plastics
… this biological self-healing motif into synthetic biomimetic polymers. These types of polymers will be used to develop components with greater fatigue life and toughness, promoting greater resource sustainability by reducing plastic consumption. The amino acid 3,4-dihydroxyphenylalanine …
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Surfactant Assisted Electrospray Ionization Time of Flight Mass Spectrometry of Synthetic Polymers
Synthetic polymers are complex mixtures which often require extensive characterization to determine chemical composition and structure. Mass spectrometric techniques have greatly enhanced the quantity, as well as the quality, of data that can be used to characterize synthetic polymers. Electrospray …
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Functional and complex topological applications of plasma polymerized ultrathin films
… study is focused on the fabrication of plasma polymerized ultrathin films and the elucidation of their unique properties with an emphasis on the solvent-less, dry polymerization process to introduce post-deposition functionality, robustness, and shape preservation. Two major classes of …
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Designing Polymer Hydrogels for Extrusion-Based Additive Manufacturing
… and materials chemistry are stimuli-responsive polymers, which change their chemical and physical properties in response to specific environmental cues. Stimuli-responsive polymer hydrogels, in particular, are seeing significant interest in extrusion-based AM for the fabrication of bespoke …
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Factors affecting the metabolism and toxicity of DEHP
… (PVC) to make them soft and flexible. PVC is synthetic polymer, widely used in medical devices such as; blood bags, intravenous tubing and intragastric feeding equipment. During use, DEHP leaches out of the devices into the patients' bodies or into the fluids stored in the PVC bags. This …
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ENHANCING THE BONDING OF SYNTHETIC POLYMERS MIMICKING MARINE BIOADHESIVES
… and each other, even when wet. In developing synthetic mimics of mussel adhesive proteins, we are incorporating simplified forms of cross-linkable monomers into synthetic polymer backbones. One such example is poly[(3,4-dihydroxystyrene)-co-styrene] in which 3,4-dihydroxystyrene can provide …
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Purification and Properties of Bacteriophage f2 Replicase
… properties of an RNA-dependent ribonucleotide-polymerizing enzyme (RNA replicase) produced during infection of E. coli with the RNA bacteriophage f2. Studies on the RNA replicase of the distantly-related bacteriophage Q3 have established the feasibility of using a simplified assay for replicase …
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Tissue engineering of co-cultured skin substitutes using biocomposite membranes based on collagen and polycaprolactone
… the collagen release rate and the content of synthetic polymer in the biocomposite samples that may be exploited for controlled presentation and release of biopharmaceuticals such as growth factors. Good compatibility of all biocomposite groups was proven by interaction with 3T3 fibroblasts, …
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