Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"synovitis"”.
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Utilizing Multitask Transfer Learning for Sonographic Rheumatoid Arthritis Synovitis Grading
… the four sonographic Rheumatoid Arthritis (RA) synovitis grades (Grade 0, Grade 1, Grade 2, and Grade 3) is a difficult problem due to the complexity of the relevant markers. Therefore, the current research proposes a Multitask Transfer Learning (MTL) framework for sonographic RA synovitis …
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Quantitative Assessment of Synovitis in Legg-Calve-Perthes Disease Using Gadolinium Enhanced MRI
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Studies on Culicoides (Diptera: ceratopogonidae) and their relationship to infectious synovitis in poultry in Virginia
… their role as potential vectors of infectious synovitis. In addition, a survey of Culicoides in Virginia was made to study their distribution, bionomics and life histories. The insects were trapped in the field, collected as larvae, and reared in the laboratory. Using light traps in chicken …
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The Effects of Epidural Deracoxib on the Ground Reaction Forces in an Acute Stifle Synovitis Model
… effects of a sodium urate crystal-induced stifle synovitis in dogs, and to compare the effects of epidural versus subcutaneously injected deracoxib. Study Design: Experimental, randomized, double-blinded, placebo controlled modified cross over design. Animals or Study Population: 24 random source …
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Studies on the transmission of the poultry disease, infectious synovitis, by using direct contact and insect vector methods
The possibilities of transmission of infectious synovitis were explored. Two types of tests, using mosquitoes as vectors, were employed. One type involved the feedings of mosquitoes on previously inoculated birds, then after a period of from zero to ninety-six hours refeeding the mosquitoes on …
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The Analgesic Effects of Epidural Ketamine in Dogs With a Chemically Induced Synovitis: A Comparison Between Pre - or Post - Injury Administration
… or after the induction of a sodium urate crystal synovitis provides analgesia in dogs. In Part I, sixteen dogs were anesthetized with propofol (4 mg kg-1 intravenously). A sodium urate crystal synovitis was induced in the right stifle and allowed to develop for 12 hours. These dogs were again …
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Quantitative Magnetic Resonance Imaging of Knee Articular Cartilage and Effusion-Synovitis: The Structural Response to Changes in Joint Loading
… articular cartilage composition and/or effusion-synovitis were examined in people with or at risk for knee OA and healthy controls, and after altering joint loads. Chapter 2 is a systematic review that studied articular cartilage composition using MRI T2 and T1ρ relaxation in patients at risk for …
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Evaluation of oral n-3 polyunsaturated fatty acid effect on the inflammatory response to a novel experimental model of synovitis in the horse
To view the abstract, please see the full text of the document.
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Equine Septic Arthritis and Serum Amyloid A
… arthritis and non-septic joint inflammation (synovitis) based on clinical signs and synovial fluid cytology alone. A rapid assay to help confirm septic arthritis would be advantageous. A new assay to quantify the major equine acute phase protein, serum amyloid A (SAA) may fulfill this need. …
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Macrophage-mediated regulation of joint homeostasis
… among different arthritic conditions is chronic synovitis. Macrophages are the main drivers of synovitis and can display pro-inflammatory (M1) or pro-resolving responses (M2). Macrophages promote joint health through phagocytic and secretory activities; however, when these functions are …
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Proteomics: A close encounter with rheumatology
… worden zowel RA als SpA gekenmerkt door synovitis, de chronische ontsteking van het synoviaal membraan. Het synoviaal membraan bekleedt het gewrichtskapsel en is verantwoordelijk voor de homeostase van het gewricht. De ontsteking van dit delicate vlies kan accuut zijn door belasting en/of …
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Studies on the differentiation of inflammatory and regulatory T-cells
… was associated with disease outcome in early synovitis patients was also studied. Although the TReg/T17 ratio did not stratify with outcome, T-cell responses to 1,25(OH)\(_2\)D\(_3\) were observed in all patients, suggesting that their VDR signalling is intact and that …
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Molecular and functional analyses of human synovial B-lymphocytes in rheumatoid arthritis
… in other cases of RA and osteoarthritis (OA) synovitis, primers specific for the CDR3 rearrangement of this hybridoma were used. The clonotypic and clone related sequences (98 per cent ± 1 per cent homology) could only be detected in synovitis of RA cases but not in OA cases indicating that …
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Investigations into the role of Toll-Like Receptors in the modulation of the inflammatory response during Osteoarthritis
… inflammatory disease, associated with synovitis of the fibroblast-like synoviocytes (FLS). FLS are sentinel cells that contribute to OA pathogenesis, through secretion of various catabolic and pro-inflammatory mediators, though the downstream stimuli which initiate and propagate the …
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The Effects of Non-Surgical Interventions on Osteoarthritis-Like Changes in the Mouse Knee
… knee OA. Taken together, these data support that synovitis and soft-tissue activation in early OA joints may precede and/or accelerate the process cartilage degeneration characteristic of progressive and late stage osteoarthritis. Intra-articular injections of high molecular weight HA one day …
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Modulation of Alzheimer’s Disease Pathology by Collagen-Induced Rheumatoid Arthritis in APP/PS1 Mice
… characteristics of RA, such as joint swelling, synovitis, and cartilage and bone degradation 4 months later. Joint pathology was accompanied by sustained induction of IL-1β and TNF-α in plasma over 4 weeks after administration of CII in CFA. In the presymptomatic stage, prior to the onset of …
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The independent and combined effects of rapamycin and metformin on naturally occurring osteoarthritis
… bone sclerosis, meniscal calcification, synovitis, and skeletal muscle dysfunction. Inhibiting the mechanistic target of rapamycin (mTOR) and stimulating AMP-activated protein kinase (AMPK) has extended lifespan and protected against post-traumatic (secondary) OA in mice. However, it …
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Combined Cell and Gene Therapy Towards the Prevention of Osteoarthritis
… showed that stkIL1R2 expressing MSCs reduced synovitis and attenuated OA in the DMM OA knee model. Therefore, IL-1β sticky trap expressing MSCs may be a potential therapeutic option to prevent or slow down the progression of OA.
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Turning Round: Optimizing the Anti-Inflammatory Properties of Equine Bone Marrow Derived Mesenchymal Stem Cells for Osteoarthritis Through Three-Dimensional Culture
… eBMSC spheroids. A model of equine LPS induced synovitis was used to investigate anti-inflammatory efficacy of spheroid eBMSCs compared to placebo or monolayer eBMSCs in vivo. eBMSCs aggregate into spheroids that have stable stem cell marker expression with increased secretion and gene …
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Synovial Fibrosis in Osteoarthritis of the Knee: Mechanism of Development and Potential Therapeutic Targets
… potential therapeutic applications in mitigating synovitis and synovial fibrosis in advanced OA.</p>
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