Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"synaptotagmin 7"”.
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Characterization of synaptotagmin 7 function in neurotransmission and its subcellular localization at synapses
… phase of SV fusion mediated by the Ca²⁺ sensor Synaptotagmin 1 (SYT1). A slower SYT1-independent asynchronous phase is also present at many synapses and has been hypothesized to be mediated by another Synaptotagmin, SYT7. To determine if SYT7 plays an evolutionarily conserved role as an …
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SNAREs in evoked and spontaneous neurotransmission
… konnten wir zeigen, dass der knock-out von Synaptotagmin-7 keinen Phänotyp in hippocampalen Neuronen besitzt. Es konnte ebenso gezeigt werden, dass SNAP-23 in der Tat mit Synaptotagmin-7 in einer lebenden Zelle interagiert, und auch, dass Synaptotagmin-7 der mutmaßliche Kalzium-Sensor für …
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Molecular genetic characterization of the Drosophila synaptotagmin family
… of intense investigation in neuroscience. The synaptotagmin family of vesicle proteins has been implicated in calcium- dependent neurotransmitter release, although Synaptotagmin 1 (Syt 1) is the only isoform demonstrated to control synaptic vesicle fusion. We have characterized the six …
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Molecular Mechanisms of Presynaptic Plasticity and Function in the Mammalian Brain
… (train facilitation; TF) of presynaptic stimuli. Synaptotagmin 7 (Syt7) has been shown to act as residual calcium (Ca$_{res}$) sensor for PPF and TF at various synapses. Syt7 also seems to be involved in recovery from depression, whereas its role in neurotransmission remains controversial. My aim …