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Showing 1 to 3 of 3 for “"synaptojanin"”.
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FREQUENCY AND AMPLITUDE CONTROL OF CORTICAL OSCILLATIONS BY LIPID METABOLISM
… phosphoinositide phosphatases namely synaptojanin 2 and SHIP1. By perturbing phosphoinositides using optogenetic methods and chemical drugs, I demonstrate that the pulses of PtdIns(4,5)P2 regulate the amplitude of cyclic membrane waves while PtdIns(3,4)P2 sets the frequency. Class I …
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Profilin II : novel functions in membrane trafficking
… disease and the phosphatidylinositol phosphatase synaptojanin were identified as new profilin II ligands, which are not found in the profilin I complex, linking this profilin isoform to lipid metabolism and disease. The second goal of this thesis was to address the question of a possible role for …
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Pil1, an Eisosome Organizer, Plays an Important Role in the Recruitment of Synaptojanins and Amphiphysins to Facilitate Receptor-Mediated Endocytosis in Yeast
… Rvs167-GFP. Furthermore, the mistargeting of the synaptojanins, Sjl1 and Sjl2, to the cytoplasm in pil1Δ cells suggests that Pil1 is required for the proper recruitment of the synaptojanins to endocytic sites. A severe motility defect of Abp1-GFP during its internalization in a codeletant of PIL1 …