Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"synaptic vesicle cycle"”.
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Genetic analysis of synaptogyrin function in the synaptic vesicle cycle
… relies on the continual replenishment of synaptic vesicles that are primed for neurotransmitter release in response to action potentials. A vast array of proteins is required to mediate synaptic vesicle biogenesis, trafficking, docking, exocytosis, and endocytosis. Synaptogyrin and …
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Molecular Anatomy of a Living Nerve Terminal: Actin and Synapsin in the Synaptic Vesicle Cycle
… is based on a series of events termed the synaptic vesicle cycle. Several molecular components contributing to the synaptic vesicle cycle are known, including the cytoskeletal protein actin and the synaptic vesicle-associated phosphoprotein synapsin. The studies presented in this thesis …
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Investigation of the physiological function of TTBK2 (tau tubulin kinase 2), a protein kinase mutated in spinocerebellar ataxia type 11 (SCA11)
… that TTBK2 operates in a distinct step of the synaptic vesicle cycle. An analysis of potential protein substrates identified synaptic vesicle glycoprotein 2A (SV2A) as a substrate of TTBK2. Phosphopeptide mapping revealed that SV2A is phosphorylated at two clusters of three highly-conserved …