Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"sympathetic neurons"”.
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Morphologic changes in preganglionic sympathetic neurons of rat following exercise and aging
Thesis (M.S.)--Michigan State University. Dept. of Anatomy, 1975
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Electrical and Optogenetic Stimulation of Sympathetic Neurons to Stabilize Blood Pressure after Acute Spinal Cord Injury
… induces pressor responses by activating ChAT+ sympathetic preganglionic neurons (SPNs) in the intermediolateral column that innerve the splanchnic vasculature. My thesis aimed to investigate whether blood pressure stability can be restored in mice during the acute phase of SCI using eSTIM, and …
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Differential regulation of herpes simplex virus-1 and herpes simplex virus-2 during latency and post reactivation in response to stress hormones and nerve trauma in primary adult sensory and sympathetic neurons
… of lifelong latency in sensory and autonomic neurons of the peripheral nervous system that innervate the site of infection. Any cellular stress trigger, ranging from external stimuli such as UV radiation or nerve injury to psychological and physiological stress, can reactivate HSV from latency …
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Mechanisms and plasticity of cold sensitivity in peripheral neurons
… involved in cold transduction in peripheral neurons. Members of the transient receptor potential (TRP) family of cation channels are currently recognised as the principal transducers of thermal stimuli in sensory neurons, and two channels, TRPM8 and TRPA1, have been implicated in cold …
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Sub threshold high frequency electrical field stimulation effect for angiogenesis and vegf expression in cardiomyocytes and heart tissue. Remodelling in the heart: impact of mechanical stretch, threshold and sub-threshold electrical stimulation on cultivated cardiomyocytes and sympathetic neurons /
… growth factor. To evaluate the response of the sympathetic system neurons to mechanical stretching in the evaluation of biologically active substances such as vascular endothelial growth and neuronal growth factors. Up to now, studies have shown that high-frequency threshold or sub-threshold …
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The Effects Of Oxidative Stress On P75ntr Signaling In Dopaminergic Neurons
… p75NTR was discovered to become activated in sympathetic neurons in response to oxidative stress induced by 4-hydroxynonenal (HNE) in a ligand-independent mechanism. Furthermore, cleavage of the receptor was demonstrated to contribute to the death of sympathetic neurons following oxidative …
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Interactions Between Microbial, Neuronal, and Immune Cells in the Digestive System
… the dynamic interplay between gut microbes, neurons and immune cells in the murine intestine during homeostasis and upon microbial perturbations. The human intestinal tract is home to ~10 trillion commensal microbes (Sender et al., 2016). The microbiota influences key physiological processes …
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Essential Function of Ghrelin in Chronic Starvation
… that depletes adrenergic neurotransmitters from sympathetic neurons, blocked the fasting-induced increase in plasma ghrelin. Thus, ghrelin secretion during fasting is induced by adrenergic agents released by sympathetic neurons which act directly on β1 receptors on the ghrelin-secreting cells of …
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The morphology, neurochemistry, and consequences of sympathosensory plexuses
The development, maintenance, and survival of neurons depend on the function of neurotrophins such as nerve growth factor (NGF). One population of neurons that rely heavily on NGF for axonal growth and survival is the postganglionic sympathetic neurons. Trauma or disease resulting in injury to the …
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The role of the ventrolateral medulla in the pressor reflex to static muscular contraction
… single unit discharge patterns in 107 of 167 VLM neurons increased by more than 70% during muscular contraction. Computer signal averaging techniques were used to determine if VLM unit discharge correlated temporally with a 2 to 6 Hz rhythm of sympathetic nerve activity. Sympathetic related …
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Neuronal regulation of haematopoietic stem cell ageing and age-related blood disorders through the microenvironment
… unique microenvironment known as ‘’HSC niche’’. Sympathetic neurons are important BM niche regulators, controlling HSC traffic in and out of the BM through the activation of β-adrenergic receptors (β-ARs). However, whether BM sympathetic-adrenergic signalling regulates other functions of HSCs …
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Plasticity of Adrenal Chromaffin Cell Function During Inflammation and Exposure to Microbe-Associated Molecular Patterns
The sympathetic nervous system (SNS) is part of an integrative network that functions to restore homeostasis following injury and infection. The SNS provides negative feedback control over inflammation through the secretion of catecholamines from postganglionic sympathetic neurons and adrenal …
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The role of autonomic neurons in the pathegenesis of herpes simplex virus infection
… investigated, especially with in sensory neurons. Another component of the peripheral nervous system (PNS), autonomic neurons, were also known to be infected with HSV productively and latently, but largely ignored because of the assumption that there is no difference in the pathogenesis of …
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REGULATION OF NEURAL CREST DEVELOPMENT REQUIRES FUNCTIONAL INTERACTIONS BETWEEN HDAC1, TFAP2A AND FOXD3
… a wide variety of cell types including glia and neurons of the peripheral neurvous system, pigment cells and elements of the craniofacial skeleton. However, the mechanisms regulating the process of neural crest cell diversification (NCCD) are incompletely understood. A number of transcription …
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Systematic Co-Culture of IPSC-CM and IPSC-AN Promote Co-Maturation In Vitro
… proper heart function. In native heart muscle, sympathetic neurons (SN) and parasympathetic neurons (PSN) modulate the beat rate of cardiomyocytes (CM) to maintain homeostasis. Pluripotent stem cells can differentiate into CM, but differentiated CMs are fetal-like, with a high beat rate, and …
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Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System
… can directly impact intrinsic enteric associated neurons (iEAN) and intestinal motility. Reciprocally, iEAN express colony-stimulating factor 1 (CSF1), which may play a role in the local maintenance and differentiation of MM. Both axes of this crosstalk occur during normal, steady-state conditions …
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The Identification of a Leptin Dependent Neural Pathway Regulating Adipose Tissue Innervation
… the underlying mechanism is not known. The sympathetic nervous system (SNS) is the major regulator of several critical steps involved in fat utilization, we therefore hypothesized that leptin might regulate the plasticity of SNS innervation of adipose tissue to promote fat usage. We first …
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Neural and Physical Niches Orchestrate Skeletal Remodelling and Promote Cartilage Regeneration
The skeleton is densely innervated by sympathetic noradrenergic and cholinergic nerve fibres. While several studies suggest the bone-catabolic nature of noradrenergic innervation in decreasing osteoblast activity and promoting osteoclastogenesis, there is little known on the development and …