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Showing 1 to 1 of 1 for “"switchable genetics"”.
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Elucidating p53’s physiological and tumourigenic roles
… suppression, I have built a unique, temporally switchable mouse model in which p53 function may be reversibly toggled between wild type and null states at will in vivo. I show that acute systemic repression of p53 in adult mice elicits no overt symptoms or somatic pathologies. However, …