Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"susceptibility to tuberculosis"”.
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Screening of the human tumor necrosis factor (TNF) gene and its receptor 1 (TNFR1) gene for DNA alterations and the subsequent investigation of these and an IL12p40 polymorphism for an association with paediatric tuberculosis
Infection with Mycobacterium tuberculosis is characterised by diverse outcomes; the majority of infected individuals remain well and yet others develop disease ranging from limited pulmonary tuberculosis to severe disseminated disease. The reasons for this diverse outcome are poorly understood, but …
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Alcohol and problem drinking as risk factors for tuberculosis
[Background] Tuberculosis is a major public health concern for South Africa which has one of the highest recorded incidence rates in the world. Previous research [1998 South African Demographic and Health Survey (SADHS)] reported a crude association between alcohol use and tuberculosis. This study …
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Immunological markers of protective immune reconstitution in HIV infected persons sensitised by Mycobacterium tuberculosis
Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide and HIV-1 co-infection is the leading cause of susceptibility to tuberculosis. Sub-Saharan Africa has a high incidence of TB-HIV-1 coinfection and the risk of TB in HIV-1 infected people is increased at all …
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In vivo effects of South African traditional medicines against Mycobacterium tuberculosis in experimental mice
… chemotherapy became available, the incidence of tuberculosis is increasing in much of the developing world and has recently re-emerged as a public health problem in industrialized countries. This problem is compounded by the increase in host susceptibility to tuberculosis caused by co-infection …
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Incidence of tuberculous infection among the native inhabitants of the gold coast and its bearing on the question of immunity
… years the proportion of deaths from pulmonary tuberculosis had far exceeded that of all other killing diseases with the single exception of non- tuberculous affections of the respiratory tract. This disease accounted for 9.9 per cent. of the total deaths in 1931, 9.2 per cent. in 1932 and 10.5 …
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Understanding functional mechanisms of genetic susceptibility to mycobacterial infection
Tuberculosis remains a major public health problem and one of the leading causes of death worldwide. Human genetic factors determine susceptibility to M. tuberculosis (M. tb) infection and predispose to clinical TB. Genome-wide association studies (GWAS) aim to discover human genes associated with …