Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 128 for “"survival time"”.
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Markov models to estimate and describe survival time and experience in cohorts with high euthanasia frequency
Unique to survival analysis of veterinary clinical data is classification of observations from euthanized animals. The first study highlighted limitations of Kaplan-Meier product limit analysis (KM) of veterinary clinical data. Three data sets with different outcome proportions (alive, …
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Sleep Disorders and Kidney Transplant Outcomes: Findings From an 18-Year (1997-2015) Historical Cohort Study
… a functioning graft during the designated study time period (January 1, 1997 to September 1, 2015, inclusive) were included (n=299). The primary independent variables, any sleep disorder and any sleep-disordered breathing disorders, were defined through a diagnosis in a subject’s medical record. …
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Concurrent Infections of SCHISTOSOMA MANSONI and TRYPANOSOMA EQUIPERDUM in Mice
… was to determine factors which may influence the survival time of mice infected with <em>Trypanosoma equiperdum</em> and the effects of <em>T. equiperdum</em> on mice infected with <em>Schistosoma mansoni</em>.</p> <p>In order to maintain experimentally obtained standard hours of survival (88 hrs) …
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Essays on investment
… to the style timing literature by quantifying survival time of style portfolio momentum and implement style timing strategies based on the mean survival time. We find that empirical survival times differ from those implied by theoretical models (Random Walk and ARMA (1, 1)) - suggesting the …
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Parametric survival models with interval censored data in determining prognostic factors of patients of lung cancer
… censored where it reflects on the uncertainty of survival time until an event occur. Survival analysis can accommodates both fixed and time varying covariates with the presence of censored data. The survival time of parametric distribution of Weibull, exponential and log-logistic were derived by …
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Concurrent Infections of TRYPANOSOMA EQUIPERDUM and TRICHINELLA SPIRALIS in Mice
… and <em>Trypanosoma equiperdum</em>, the survival times vary in the early stages of the <em>Trichinella</em> infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This decrease is probably due to intestinal tissue …
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A pilot study of fatigue and situation awareness during simulated small satellite operations
… avoidance scenario. Dependent measures included survival time, strategy used, fuel usage, secondary task reaction time, and responses to a situation awareness questionnaire. An ANOVA found significant interaction effects of sleep protocol order and fatigue state on survival time (p=0.008). For …
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Evaluation of the Effectiveness of a Feline Toxoplasma Vaccine in Reducing the Exposure of Swine to Toxoplasma Gondii
… prevalence in cats, and (5) decreased oocyst survival time. Simulations were run for 10 years, with a weekly interval. Elimination of T. gondii in finishing pigs increased with a decrease in oocysts survival and a decrease in the number of cats in the farm. T. gondii prevalence in finishing …
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LOCOREGIONAL DELIVERY OF UNMETHYLATED CPG-OLIGODEOXYNUCLEOTIDES TO CANCER THERAPY: PRECLINICAL STUDIES
… 4 weeks, CpG-ODN had only a marginal effect on survival time, whereas administration 5 days/week for 3 or 4 weeks led to a significantly increased survival-time as compared to controls and completely controlled ascites growth without apparent toxicity, although a disorganization of lymphoid …
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Continuous low dose rate irradiation of the rat brain
The reported median survival time for patients who are diagnosed with high grade astrocytomas and who undergo postoperative radiotherapy is of the order of 24 to 40 weeks. The course of radiotherapy administered to these patients takes up a considerable portion of their expected survival time. …
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In Vivo Kinome Screen Reveals Non-Canonical Cdk-Driven Metabolic Adaptation In Brain Metastasis
… pools led to decreased brain metastasis-specific survival in nude mice, shortening survival time by up to 50% relative to controls. Targeted next-generation sequencing (NGS) was performed to analyze pre- and post-injection MDA-MB-231 cells, thus identifying 31 kinases that were significantly …
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Χορήγηση φαινυτοΐνης για την προφύλαξη του εγκεφάλου από υποξία
… administration (50mg/Kg) during hypoxia. Survival time and histological study of brains under light microscope were studied. The mice were divided into nine groups. Am group: Hypoxia until death. Bm group: Normal saline administration 20 min before hypoxia until death. Cm group: Phenytoin …
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Survival Prediction For Brain Tumor Patients Using Gene Expression Data
… of cancer in humans, with an estimated median survival time of 12 months and only 4% of the patients surviving more than 5 years after disease diagnosis. Until recently, brain tumor prognosis has been based only on clinical information such as tumor grade and patient age, but there are reports …
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The Effect of Leucogenenol on Classical Chemotherapy and Immunotherapy of Friend Virus Disease
… investigated. Three parameters of the disease, survival time, ratios of spleen and liver weight to total body weight and periodic differential counts of peripheral blood were studied and analyzed. Findings. Although Methotrexate significantly prolonged survival time in animals thus treated, the …
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Identification of the presence and activity of the JAK-STAT pathway in canine solid tumors
… Signalment, treatment information, and survival information was obtained from the medical record for each case. Results: Tumor samples were scored for percent positive neoplastic cells. Positive staining was seen for all antibodies in all tumor types, with expression of JAK1, STAT3, and …
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The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation.
… may not reflect the concentration at the time of death. Tissues that are located away from central drug reservoirs and that lack esterase activity, e.g. muscle and vitreous humour (VH), have the potential to provide more reliable post-mortem toxicological specimens. In the absence of a …
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DWCox: A density-weighted Cox model for outlier-robust prediction of prostate cancer survival
Reliable predictions on the risk and survival time of prostate cancer patients based on their clinical records can help guide their treatment and provide hints about the disease mechanism. The Cox regression is currently a commonly accepted approach for such tasks in clinical applications. More …
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Application of Informatics Tools to Facilitate the Practice of Precision Medicine with Genomic Testing and Clinical Data
… Through multivariate statistical models and vi survival analyses, we demonstrated the impact of various clinical and biomolecular variables on patient survival. Our results showed patients experiencing immune related adverse events (irAEs) and their timing had a significant impact on patient …
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Local exposure and efficacy of a reservoir-based drug delivery device
… cause of mortality is tumor recurrence, often centimeters away from the original lesion site. Current treatments involve systemic radiotherapy or chemotherapy, and improve median survival time by only a few months. Efforts to develop local treatment modules are motivated by the fact that patients …
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Analysis of outcomes following emergency admission in patients with dementia and/or cognitive impairment and/or delirium
… Tests were conducted to describe the median survival time and survival difference. Cox’s proportional hazards regression model was employed to investigate the association between death and survival time with multiple predictors. To check the validity of the survival model, Kolmogorov-Type …
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