Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1131 for “"surrogate"”.
-
Surrogate travel via optical videodisc
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1978.
-
Slipping on the strongest surrogate constraint
Includes bibliographical references.
-
Search for valid surrogate endpoints: review of current evidence and development of practical strategies for surrogate evaluation
… pursuit of more quickly available treatments, surrogate endpoint evaluation has become a vital part of drug development. Despite the increasing uptake of surrogate endpoints and the large number of statistical methods proposed to evaluate a surrogate, there is still no consensus on how to …
-
Surrogate endpoints of survival in metastatic carcinoma
… quantified (1). Using an early proxy, or a surrogate endpoint, in place of the direct endpoint of overall survival (OS) could theoretically shorten the duration of RCTs and minimise the exposure of patients to ineffective or toxic treatments (2, 3). This thesis examined the relationship …
-
Surrogate Model Optimisation for PWR Fuel Management
… to investigate. In this thesis, the method of surrogate model optimisation is adapted to PWR loading pattern generation. Surrogate models are developed based around three approaches: deep learning methods (convolutional neural networks and multi-layer perceptrons), the fission matrix and …
-
TCAD-Informed Surrogate Models of Semiconductor Devices
… We use Semiconductors.jl to implement performant surrogate models that approximate the behavior of fine-grained technology computer-aided design (TCAD) device models using a coarsified grid. The resulting surrogate models are shown to approximate the current-voltage characteristics of the …
-
Uncertainty-Integrated Surrogate Modeling for Complex System Optimization
<p>Approximation models such as surrogate models provide a tractable substitute to expensive physical simulations and an effective solution to the potential lack of quantitative models of system behavior. These capabilities not only enable the efficient design of complex systems, but is also …
-
Rodent testing device surrogate for shockwave blast testing
Many laboratories around the world are conduct shockwave blast injury tests on rodents to simulate blast traumatic brain injury (TBI). Each of these laboratories has different techniques for creating the shockwave blasts as well as positioning the rats. There is no device to determine whether or …
-
Surrogate modeling for large-scale black-box systems
… equations are unavailable. For such systems, surrogate models are critical for many applications, such as Monte Carlo simulations; however, existing surrogate modeling methods often are not applicable, particularly when the dimension of the input space is very high. In this research, we …
-
Surrogate-based optimization of a BioMEMs microfluidic weir
… design optimization computationally tractable a surrogate is derived; that is, a model that provides an accurate approximation to the input/output map of the simulation but that is much cheaper computationally to evaluate.
-
Linear Parameter Uncertainty Quantification using Surrogate Gaussian Processes
We consider uncertainty quantification using surrogate Gaussian processes. We take a previous sampling algorithm and provide a closed form expression of the resulting posterior distribution. We extend the method to weighted least squares and a Bayesian approach both with closed form expressions of …
-
Surrogate-based optimization using multifidelity models with variable parameterization
… such optimization computationally intractable. Surrogate-based optimization (SBO) - optimization using a lower-fidelity model most of the time, with occasional recourse to the high-fidelity model - is a proven method for reducing the cost of optimization. One branch of SBO uses lower-fidelity …
-
Surrogate Models for Transonic Aerodynamics for Multidisciplinary Design Optimization
… coefficients. These points are used to generate surrogate models which can be used for the two-dimensional aerodynamic calculations required by the MDO computational design environment. Strip theory is used to relate these two-dimensional results to the three-dimensional wing. Models are …
-
Enhancing the mechanical properties of a hydroxyapatite-collagen bone surrogate
<p>The synthesis of biomimetic hydroxyapatite-collagen composites is desirable from the perspective of graft elimination and load-bearing support when treating damaged or diseased bone. Bone is an organized network of carbonated hydroxyapatite mineralized collagen, whose strength and toughness is …
-
HUMAN DPP4/CD26 TRANSGENIC MICE AS SURROGATE MODELS FOR MERS
… globin splicing and polyadenylation sites, as surrogate models for MERS-CoV infections. We showed that one lineage (line 52) of Tg mice globally expressing hDPP4 is highly susceptible to intranasal (i.n.) challenge with a high-dose (i.e., 106 50% tissue culture infectious dose [TCID50]) of …
-
Development of a biofidelic cranial bone surrogate using additive manufacturing
Cranial bone surrogates are widely used in many applications, including mechanical, impact and blast, and biomedical testing. Such surrogate models often attempt to mimic the properties of bone to achieve best results. This research focuses on using additive manufacturing to develop a 3D printed …
-
Machine Learning based Surrogate Modeling of Electronic Devices and Circuits
L'abstract è presente nell'allegato / the abstract is in the attachment
Page 1 of 57