Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 127 for “"surgical resection"”.
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Population-based outcomes in pancreatic cancer: Improvements in survival, underutilization of surgical resection for early stage disease, and regionalization of care
… men and women in the United States. Currently, surgical resection remains the only hope for long-term survival in patients with this aggressive cancer. The work defined in this thesis provides population-based data on patients with pancreatic cancer that can be used to improve outcomes and set …
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Pulmonary aspergillomata: an assessment of clinical outcome after surgical resection and of the most immune response to aspergillus infection at cellular level
A pulmonary aspergilloma, one of the forms of pulmonary disease caused by the ubiquitous fungus Aspergil/us species, is a secondary fungal infection imposed on pre-existing pulmonary disease. It is commonly associated with haemoptysis, which may be life-threatening 8•9•12•17- 19 •30. Colonisation …
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Adjuvant Chemoradiation Therapy in Gallbladder Cancer
… for adjuvant chemoradiation therapy after surgical resection have not yet been determined. We aimed this study to elucidate the effectiveness of adjuvant chemoradiation therapy according to TNM stage for gallbladder cancer. Between March 2001 and March 2009, 100 patients with gallbladder …
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간세포암 환자의 치료에 있어 수술적 절제술과 간동맥 화학색전술 치료요법에 따른 생존율 비교 연구
… survival periods between the group who underwent surgical resection and the Transcatheter Arterial Chemoembolization group who treated with transcatheter arterial chemoembolization (TACE) which was a non-operative method were investigated and compared. Further, statistical significances in the …
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Effectiveness of palliative measures in treatment of dysphagia of cancer of the oesophagus
… is no exception. For patients stage III/IV, surgical resection of the tumour was attempted if possible. For advanced stage oesophageal carcinoma, that is stage III/IV, surgical resection with curative intent was not performed. The cardinal symptom of oesophageal carcinoma was then treated …
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Surgical Outcomes for Solid Pseudopapillary Neoplasm of Pancreas
… potential. This study was designed to evaluate surgical outcome of solid pseudopapillary neoplasm (SPN). Methodology: From Between January 1994 to November 2013, 41 patients were diagnosed with SPN of the pancreas at Ajou University Medical Center and underwent surgical resection. Results: Of …
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Trends in Receipt and Timing of Multimodality Therapy in Early-Stage Pancreatic Cancer
… Therefore, multimodality therapy with surgical resection and chemotherapy is the standard of care for locoregional disease. We described treatment patterns and time trends with regard to age and treatment center in the receipt of multimodality therapy. Methods We used the National …
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Trends in Receipt and Timing of Multimodality Therapy in Early-Stage Pancreatic Cancer
… Therefore, multimodality therapy with surgical resection and chemotherapy is the standard of care for locoregional disease. We described treatment patterns and time trends with regard to age and treatment center in the receipt of multimodality therapy. Methods We used the National …
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RAPID DETECTION OF THE IDH1 R132H MUTATION IN GLIOMAS USING RECOMBINASE POLYMERASE AMPLIFICATION
… of the IDH1-R132H mutation. Diagnosis guided resections has potential to extend life expectancy up to 10 years. Our assay identifies the status of the IDH1-R132H mutation which has a characteristic of slower growth. Surgery requires a delicate balance between resecting more of the tumor and …
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Pharmacogenomic profiling and clarification of the role of the mismatch repair genes in response to the chemotherapeutic agent 5-Fluorouracil in a South African colorectal cancer cohort
… recurrence, respectively, after curative surgical resection. The main chemotherapeutic agent is 5-Fluoroucacil (5-FU). Studies have attempted to elucidate whether the MMR status of a colorectal cancer (CRC) cohort will define a response to 5-FU therapy. However, no difference in long term …
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Trends and Comparative Effectiveness in Treatment of Stage IV Colorectal Adenocarcinoma
… modalities include systemic chemotherapy, resection of the primary tumor, and, in select cases, resection of metastatic disease. Historically, stage IV disease was first managed with surgical resection to prevent complications such as obstruction, bleeding, and perforation prior to starting …
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Trends in Receipt and Timing of Multimodality Therapy in Early Stage Pancreatic
… Therefore, multimodality therapy with surgical resection and chemotherapy is the standard of care for locoregional disease. We described treatment patterns and time trends with regards to age and treatment center in the receipt of multimodality therapy. METHODS: We used the National …
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PERSPECTIVES ON THE CLINICAL APPLICATION OF LEWIS ANTIGENS IN PANCREATIC CANCER: TOWARDS A PERSONALIZED TUMOR MARKER STRATEGY
… of patients. Methods. Serum and fragments of surgical resection of PDAC patients are being collected. ELISA was performed on sera of 118 patients and 52 healthy controls, using anti-CA19.9, anti-Lea and anti-Leb antibodies. Real Time PCR (qPCR) was performed on cDNA of 14 tissue specimens …
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Hsp27 and Chemotherapy-Induced Autophagy As Biomarkers In Osteosarcoma
… multi-agent chemotherapy combined with surgical resection, a significant fraction of patients with localized disease relapse after optimal treatment. We evaluated the occurrence of cytoplasmic LC3B (light chain 3B)-positive puncta (a marker of autophagy) and presence of HSP27 (heat shock …
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Learning risk models for pancreatic cancer from electronic health records
… 45,750 deaths in 2019. Of all treatments, surgical resection provides the best survival rate for pancreatic cancer. This is not feasible for the majority of pancreatic cancer patients, whose cancer is typically not diagnosed until the tumor is unresectable. Most symptoms of pancreatic …
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Autologous intestinal lengthening procedures for short bowel syndrome. A systematic review of clinical effectiveness and an assessment of their utility for adult and paediatric patients with intestinal failure in the UK
… bowel syndrome (SBS) results from surgical resection, congenital defector disease-associated loss of absorption and is characterized by the inabilityto maintain protein-energy, fluid, electrolyte or micronutrient balances whenon a conventionally accepted, normal diet 1 . In order to …
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Quantitative multi-modal analysis of pediatric focal epilepsy
… with medically refractive focal epilepsy, surgical intervention to remove the epileptic foci is often the last alternative for permanent cure. The success of such surgery is highly dependent on the doctor's ability to accurately locate the epileptogenic region during the pre-surgical …
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Clinical Characteristics of Struma Ovarii
… The treatment of benign struma ovarii is surgical resection only. The cases of malignant struma ovarii may need adjuvant treatment. But recurrence are by no means common.
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Αvβ8 Integrin Interacts With Rhogdi1 to Regulate Rac1 and Cdc42 Activation and Drive Glioblastoma Cell Invasion
… growth behaviors that are major impediments to surgical resection and targeted therapies. Adhesion and signaling pathways that drive GBM cell invasion remain largely uncharacterized. Here we have utilized human GBM cell lines, primary patient samples, and pre-clinical mouse models to demonstrate …
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Detection of Novel Genomic Markers for Predicting Prognosis in Hepatocellular Carcinoma Patients by Integrative Analysis of Copy Number Aberrations and Gene Expression Profiles: Results from a Long-Term Follow-Up
… recurrence in patients with HCC who underwent surgical resection.
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