Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"supraoptic nucleus"”.
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Part I: the effects of the nature of respired gases on the pulmonary vascular bed with reference to the effects of carbon dioxide, oxygen and nitrogen; Part II: changes in renal function due to the action of certain drugs upon the hypothalamus
… neurohypophysis is innervated from cells in the supraoptic nucleus; and that the integrity of the nervous connections between the supraoptic nucleus and the neurohypophysis is essential for the normal control of the rate of 'urine secretion.
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State-dependent changes in astrocyte regulation of extrasynaptic NMDA receptor signaling in neurosecretory neurons
… by activation of eNMDARs in hypothalamic supraoptic nucleus (SON) neurons. We found that extracellular glutamate of a non-synaptic origin activates eNMDARs to mediate a persistent excitatory current (termed tonic INMDA), which tonically stimulates neuronal activity. Pharmacological …
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Measurement of neuropeptides: From presence to release
… of the regions of interest, the suprachiasmatic nucleus and supraoptic nucleus, were observed. The final study involved creation of a peptide database for the hippocampus through high resolution mass spectrometry with which to reference microdialysate peptides. The rats were also exposed to …
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Characterizing cerebellin-short, a novel circadian peptide, in the rat suprachiasmatic nucleus
… cycle, are orchestrated by the suprachiasmatic nucleus (SCN) located in the hypothalamus. Mass spectrometry peptidomics of the SCN identified the small peptide cerebellin-short (SGSAKBSAIRSTN) consisting of 15 amino acids, which is released from the SCN in circadian fashion. Cerebellin-short is …
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Diurnal and stimulated astrocyte morphology dynamics in the rodent central nervous system
… dentate gyrus (DG) and suprachiasmatic nucleus (SCN). Glial fibrillary acidic protein (GFAP) branch terminal-points are significantly less numerous in the DG than the SCN. Terminal-points increase and decrease in complexity throughout the day-night cycle. Branching peaks at early night …
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Naturally occurring variations in defensive burying behavior are associated with differences in central neuropeptide expression in the male rat
… higher levels of AVP and OT mRNA within the supraoptic nucleus and subregions of the paraventricular nucleus of the hypothalamus responsible for neuroendocrine and autonomic function. CRH mRNA levels did not vary as a function of burying activity in the central nucleus of the amygdala, the …
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Neurochemical and functional characterisation of the Melanin-concentrating hormone system in the rat brain
… hormone and neuropeptide Y in the arcuate nucleus. Additionally, MCHR-1 IR was co-localised with the neuropeptides vasopressin and oxytocin in magnocellular neurons of the supraoptic and paraventricular hypothalamic nucleus and corticotrophin releasing hormone in the parvocellular division …
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Ciliary neurotrophic factor signaling in the magnocellular neurosecretory system : mechanisms of neuronal survival and sprouting
… system, CNTF is up-regulated in the supraoptic nucleus (SON) that undergoes a collateral sprouting response and this increase is not due to heightened neurosecretory activity. Moreover, we demonstrated a reduction in the protein levels of the CNTF specific receptor, CNTFRa, in the …
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Investigating mechanisms and biological functions of the bHLH/PAS transcription factors SIM1 and ARNT2
… predominately expressed in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus. SIM1 has been established to be essential in the developing hypothalamus and has a physiological role in appetite control during adulthood. Haploinsufficiency of Sim1 in mice results in …
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PIP2 Modulation of Afterhyperpolarizations in Magnocellular Supraoptic Neurons
… AHP mechanisms between OT and VP neurons of supraoptic nucleus. </p>
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Sampling strategies for characterization of neuropeptides using mass spectrometry and functional implications into cell-cell signaling
… of tissues. The magnocellular neurons of rat supraoptic nucleus in tissue and cell culture served as the main model to study neuropeptides, in addition to hippocampal neurons and mouse embryonic pituitaries. The neuropeptidomcis studies described here use different extraction methods on tissue …
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The role of notch signaling in the development of the hypothalamic-pituitary axis and arcuate nucleus
… neurons from the hypothalamic paraventricular nucleus (PVN) and supraoptic nucleus (SON). As the pituitary develops, signals from the hypothalamus are necessary for pituitary induction and expansion. Little is known about the control of cues that regulate early embryonic signaling between the …