Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"supramolecular structure"”.
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Supramolecular Structure-Enabled Delivery of Porphyrin to Glioblastomas Beyond the Blood-Brain Barrier
… the drug delivery advantages of porphyrin supramolecular chemistry to address this limitation through the conception of two new platforms: porphyrin apolipoprotein E3 (apoE3) lipid nanoparticles (pyE-LNs) and 2) porphyrin microbubbles (pMBs). PyE-LNs were designed to exploit apoE3’s …
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Design and synthesis of a new polymer: study of supramolecular structure and functional properties
Un nuovo polimero appartenente alla famiglia dei poliarilacetileni, portatore di ramificazioni basate sulla presenza di cavità calix[5]areniche, è stato sintetizzato e caratterizzato. La tecnica della titolazione NMR ha portato a riconoscere la presenza di diverse strutture supramolecolari in …
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Nanocellulose: Preparation, Characterization, Supramolecular Modeling, and its Life Cycle Assessment
… this study was to understand the formation and supramolecular structure of MT nanocellulose and contribute to the knowledge of native cellulose structure. The research involved four major bodies of study: preparation of MT nanocellulose, characterization of MT nanocellulose, modeling wood …
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Ferrocene-derived Heterobimetallic Supramolecular Architectures: Synthesis, Guest Encapsulation and Stimulus-Responsive Studies
Metallosupramolecular architectures are increasing in popularity due to their range of applications and ease of self-assembly. Many are able to readily change their shape and/or function in response to external stimuli and have the ability to encapsulate guest molecules within their internal …
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Synthesis of guanidinium-functionalized amphiphiles for the exploration of chaotropic supramolecular nanoribbons
… to synthesize complex, chemically diverse structures with molecular length scales. Supramolecular self-assemblies comprised of amphiphilic molecules have been engineered to achieve diverse applications, from drug delivery to 3D printing. The design of the component molecules in engineered …
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Structure, dynamics and applications of peptide-based nanomaterials
… peptides can readily self-assemble into ordered structures on the nanometer length scale. The design rules for these constructs are not fully understood yet, which is a key issue in engineering new functional nanomaterials. This thesis discusses how infrared spectroscopy and computational …
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A structural database for pharmaceutical salt selection
… of the relationships between molecular and supramolecular structure and properties and the stoichiometry and ionisation state of the resultant crystalline solid. Presented in this work is a structural database containing 110 novel multi-component crystalline systems produced by the …
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Characterization of the large diameter fibers in egg case silk : identification of a core fibroin, TuSp1, and localization of fibroin-like molecules, ECPs, from the black widow spider, latrodectus hesperus
… role for the ECPs, providing clues regarding the supramolecular structure of egg case fibers.</p>
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Synthesis, characterization, and evaluation of photo-active amphiphiles for gene delivery applications
… with the anionic nucleic acid backbone to form a supramolecular structure (lipoplex). This complex allows the nucleic acid to be protected from enzymatic degradation during transport and interacts with the cell membrane to facilitate internalization by endocytosis. A limitation of current systems …
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Investigação de redução da cristalinidade da celulose sob a influência de diferentes misturas eutéticas.
… cellulose is not a trivial process, due to its supramolecular structure which prevents the process from being carried out in conventional solvents. This work studied the reduction of the crystallinity of commercial cellulose and sugarcane bagasse in different types of eutectic mixtures: lactic …
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Excitons in Self-Assembled Hybrid Systems of Molecular Aggregate Light-Harvesting Nanotubes: Charge-Transfer Substrates and Solution-Stabilized Nanocomposites
… responsible for the remarkable effciency of supramolecular light-harvesting aggregates within photosynthetic organisms. Despite tremendous progress towards a deeper understanding of these photosynthetic complexes, as well as progress in the development of organic solar cells, the possibility …
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Design of Collagen-Mimetic Peptides
… protein is its remarkable ability to form supramolecular structures through self-assembly and/or through interactions with other biomolecules. One typical example of such supramolecular structure is the fibrils of collagen types I, II and III of the connective tissues. These fibrils have …
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Preparation, characterisation and structural analysis of salts and co-crystals of organic compounds
… in the pharmaceutical industry.<br/>The novel structures of 42 salts, 11 co-crystals and 6 mixed co-crystal/salt systems have been prepared and characterised using single crystal X-ray diffraction. Together with the binary compounds already present on the CSD, this has provided the opportunity …
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Synthetic Ion Channels From Lipophilic Guanosine Derivatives
… transmembrane pore(s) could be envisioned as a supramolecular structure with hydrophobic walls of bis-lithocholate linker and a central pillar of a cation-filled G-quadruplex. The use of a bis-urea functionality in the bis-lithocholic acid linker generated guanosine-sterol conjugate 4-1. The ion …
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BIOMOLECULAR PRINTING FOR ARTIFICIAL LIFE-INSPIRED COMPARTMENTS AND SINGLE-CELL ARRAYS
… of pH-sensitive di-block copolymers of general structure mPEGxPDEAMAy-Br, were synthesized by the atom transfer radical polymerization (ATRP), a quasi-living radical polymerization reaction. The synthesized copolymers are water soluble at acidic pH ( ~ 2 ) and can self-assemble into polymeric …
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Functional organic thin films under extreme confinement
… arise as the bonds that hold entities in the supramolecular structure of organic molecules are significantly weaker. My thesis aims to crystallize extremely confined thin films of two functional materials, active pharmaceutical ingredients (APIs) and conjugated polymers, and then to explore …
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Controlling the Morphology of Supramolecular Nano- and Microfibers by Self-Assembly and Electrospinning
… preparation, characterization and comparison of supramolecular nano- and microfibers of 1,3,5-benzene- and 1,3,5-cyclohexane-trisamides using two routes: self-assembly from solution as bottom-up approach and melt electrospinning as top-down approach. The design and the controlled fabrication of …