Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"suppressor analysis"”.
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Family and tumour studies in breast and oesophageal cancer
… susceptibility. The initial area was the genetic analysis of a recently mapped breast cancer susceptibility locus, BRCAl, in a number of breast and breast-ovarian cancer families. In the largest of the ICRF families studied (BOV3), linkage to the long arm of chromosome 17 was confirmed and a …
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Genetic analysis of RNA polymerase/transcriptional activator interactions at thepepT promoter of S. typhimurium
… direct interactions with FNR. We reasoned that suppressor analysis might be a useful approach to identifying regions of FNR that are involved in interactions with RNA polymerase. Reversion of the G311E and G311R mutations led to the isolation of six mutations (E47K, T80I, A172V, A172T, V208A, …
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An RNA-interference-based platform for genome analysis and engineering in Saccharomyces cerevisiae
… of yeast genome, and was employed to perform a suppressor analysis of the yku70 knockout. A colony-size based screening method was used to identify two known and three novel knockdown modifications that can alleviate the growth arrest of the Δyku70 strain at higher temperature. Further analysis …
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Genome engineering in saccharomyces cerevisiae
… of the yeast genome, and employed to perform a suppressor analysis of a telomere-defect mutation yku70Δ. Two known and three novel knockdown modifications were identified to alleviate the growth arrest of the Δyku70 strain at higher temperature, confirming the effectiveness of our RNAi library …