Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"support cells"”.
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Adeno-Associated Mediated Transduction of Sensory Epithelia Within the Guinea Pig Cochlea
… often caused by the degeneration of the sensory cells, called hair cells, found within the cochlea. Hair cell damage can result from factors such as disease, ototoxic insult, excessive noise and age. Because treatments for hearing loss are limited, scientists are looking to the use of transgene …
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Adeno-Associated Mediated Transduction of Sensory Epithelia Within the Guinea Pig Cochlea
… often caused by the degeneration of the sensory cells, called hair cells, found within the cochlea. Hair cell damage can result from factors such as disease, ototoxic insult, excessive noise and age. Because treatments for hearing loss are limited, scientists are looking to the use of transgene …
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Spatial Expression Patterns of theSnmp Gene Family In Drosophila Melanogaster
… we show that SNMP1 expresses in neural and support cells of the antennae as is consistent with the aforementioned studies. However, it is also shown that SNMP1 expression is not limited to the antennae, but extends to support cells associating with gustatory neurons in the periphery, arguing …
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The canonical Wnt signaling pathway affects regeneration of mechanosensory hair cells in Danio Rerio
In vertebrates, mechanosensory hair cells are located in the inner ear and mediate hearing. When damage to these specialized cells occur, it leads to irreversible hearing loss. Not only do aquatic vertebrates have inner ear hair cells, but mechanosensory hair cells are also found in the lateral …
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Engineered, perfusable, human microvascular networks on a microfluidic chip
… Finally, we explored the potential use of stem cells for engineering microvascular networks in our system. We found that human mesenchymal stem cells can act as secondary, support cells during microvascular network formation.
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The Intricate Molecular Landscape of Insect Chemosensation: The Sensory Neuron Membrane Protein Gene Family
… in the antenna and express in both neurons and support cells (Forstner et al., 2008). In Drosophila melanogaster, the SNMP-1 orthologue CG7000 has been shown to be essential for the detection of the pheromone cis-vaccenyl acetate (Benton et al., 2007; Jin et al., 2008). The D. melanogaster …
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Mechanisms Mediating Adaptive Presynaptic Muting Induction
… terminal. I also found that astrocytes, support cells in the nervous system that have garnered attention recently for their ability to modulate neuronal function, were required for the proper development of presynaptic muting in hippocampal neurons. Soluble factors released by astrocytes …
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Regulation of the development and regeneration of the zebrafish posterior lateral line
Mechanosensory hair cells located in the inner ear mediate the sensations of hearing and balance. If damaged, mammalian inner ear hair cells are unable to regenerate, resulting in permanent sensory deficits. Damage to hair cells can arise from multiple factors such as high decibel and prolonged …
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Amyloid-beta signaling in physiology and pathology: from astrocytes to SUMO
… and memory. Astrocytes, as crucial glial support cells with roles in modulating synaptic transmission, are likely cellular candidates for participating in this type of physiological Abeta signaling. To test this hypothesis, primary cultures of murine astrocytes were exposed to exogenous …
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THE MANY FACES OF REGENERATION: ENGINEERING MULTIFUNCTIONAL SCAFFOLDS FOR CRANIOMAXILLOFACIAL APPLICATIONS
… from biodegradable materials that temporarily support cells as they grow new bone tissue. The scaffolds can be made of different materials and can be customized to fit the shape of a patient’s defect. The use of additive manufacturing technologies to fabricate these constructs gives great …
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Fabrication and Optimisation of Collagen Scaffolds for Muscle Cell-Supported Angiogenesis
… development of 3D collagen scaffolds capable of supporting differentiated muscle cell populations with the potential for vascularisation. Collagen I scaffolds with varying internal architectures were fabricated and characterised, cell-material interactions were assessed in both 2D and 3D, and …