Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"superoxide anion"”.
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Investigation of Haemophilus somnus Virulence Factors: Lipooligosaccharide Sialylation and Inhibition of Superoxide Anion Production
… significantly (P <0.001) inhibited production of superoxide anion (O2-) by bovine mammary and alveolar macrophages as well as by polymorphonuclear leukocytes. Inhibition of O2- production was time- and dose-dependent and did not occur after incubation with Escherichia coli, H. influenzae, or …
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Functional characterization of equine neutrophils in response to calcium ionophore A23187 and phorbol myristate acetate
… Neutrophil aggregation, degranulation, and superoxide anion production were evaluated in assay systems which had previously been established to guantitate PMN function. Dose-response curves for A23187 and PMA were derived for the three functions. Results indicate that equine PMN aggregation …
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Characterization of the Beta-2 Adrenergic Receptor Mechanism in Bovine Neutrophils, and Some Effects of Inflammatory Stimuli on its Function
… monophosphate (cAMP) levels and suppress superoxide anion production, and 3) the beta2-adrenergic receptor mechanism is dysfunctional following exposure to inflammatory stimuli. Using the nonselective beta1- / beta2-adrenergic receptor antagonist [3H]CGP-12177 we observed a maximum …
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The Role of Reactive Oxygen Species in Near-Ultraviolet (320-400 NM) Light Inactivation of Escherichia Coli
… reactive species such as singlet oxygen and superoxide anion produced during exposure to near-UV.
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Reactions of graphene oxide and buckminsterfullerene in the aquatic environment
… reactive oxygen species (ROS), including superoxide anion (O2˙–)and hydrogen peroxide (H 2O2) when exposed to the same lamp light, under oxic conditions. The color of the GO suspension progressed from pale to dark brown during the photoreaction process, consistent with changes in the …
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Computational Evaluation of Mechanistic Pathways of Action of Superoxide Dismutase
… studies on thermodynamics of dismutation of superoxide anion radicals (O<sup>2-</sup>) to hydrogen peroxide and molecular oxygen was conducted with various theoretical models using a variety of basis sets. The computational models include semi-empirical, Hartree-Fock and density functional …
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Free radical formation and DNA damage in the cytotoxicity of alkylaminoanthraquinone antitumour agents.
… as evidenced by stimulation of NADPH oxidation, superoxide anion formation and hydroxyl radical formation associated with generation of a drug free radical in MCF-7 S9 cell fraction. Furthermore, DOX formed a free radical, stimulated oxygen consumption and produced hydroxyl radicals in intact …
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Metal induced degradation of leather
… and V(IV) species are oxidised by air, producing superoxide anion. Subsequently Fe(III) and V(V) are reduced back to the lower oxidation states by the o- diphenol moieties of tannins. In this way, the metal ions act as catalysts for the oxidation of tannins.<br/><br/>Autoxidation of Fe(II) and …
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Anti-oxidant Action and Anti-aging Activity of Phenylpropanoid Compounds
… xanthine oxidase activity, NBT/xanthine oxidase superoxide scavenging assay. In cell system superoxide production using DHE, H₂O₂ production using DCF-DA and hydroperoxide production using DHR were checked. In order to find out the effects of anti-inflammatory activity, histamine assay, …
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CDDO-ME induces apoptosis in breast cancer cells via Ca2+ influx-mediated dilation of endoplasmic reticulum and c-FLIP downregulation
… 9 G.Measurement of ROS and mitochondrial superoxide anion 9 H.Measurement of cytosolic and mitochondrial Ca² levels 9 I.shRNA-mediated knockdown of proteins 10 J.Transmission electron microscopy 10 K.Reverse transcriptionPCR analysis 11 L.Statistical analysis 12 III. RESULTS 13 …
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Loperamide enhances bortezomib-mediated cell death in colon cancer cells
… reticulum 10 G. Measurement of mitochondrial superoxide anion 10 H. Measurement of cytosolic and mitochondrial Ca² levels 11 I. Small interfering RNAs 11 J. shRNA-mediated knockdown of proteins 12 K. Aggresome staining 12 L. Flow cytometry for the analysis of DNA contents 13 M. Clonogenic …
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Photochemistry of single-walled carbon nanotubes in the aquatic environment, and their extraction from soils
… Singlet oxygen (<sup>1</sup>O<sub>2</sub>), superoxide anion (O<sub>2</sub>·<sup> -</sup>), and hydroxyl radicals (·OH) under the 280-nm cutoff filter, whereas there was a much slower rate of formation of singlet oxygen (<sup> 1</sup>O<sub>2</sub>) and superoxide anion (O<sub>2</sub>·<sup> …
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The effects of ultraviolet-B radiation on antioxidant status and survival in the zebrafish.
… suggests a UV-B-mediated increase in cytosolic superoxide anion radicals (O$\sb2\sp-$) and hydrogen peroxide. Newly fertilized eggs exposed to ambient UV-B for the duration of the hatching period exhibited 1.68% hatching success. Newly hatched larvae were observed to be more sensitive to UV-B …
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Somatolactogenic hormones and interferon-gamma as regulators of neutrophil activation
… and humans to kill Escherichia coli and secrete superoxide anion (O$\sb2\sp-$) after stimulation with phorbol myristate acetate (PMA). GH, as well as its growth promoting peptide, insulin-like growth factor-I (IGF-I), were both comparable to IFN-$\gamma$ in augmenting the secretion of O$\sb2\sp-$ …
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Benzoic acid regulates the physio-biochemical responses of chia (Salvia hispanica L.) seedlings under salinity stress
… osmotic stress-induced damage by reducing superoxide anion (O₂˙⁻) levels, altering total phenolic content (TPC) and total flavonoid content (TFC), and preventing the increase in cell death, observed under 100 mM NaCl. These results suggest that exogenously applied benzoic acid enhances chia …
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Diffusion and reaction of nitric oxide in cell cultures
… during its reaction with molecular oxygen or superoxide anion (O2-)- It is not technically feasible to monitor the concentrations of these species under most conditions of interest, yet assessing the amounts of these species reaching target cells is essential to correlate levels of toxicity …
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Spontaneous tone in deoxycorticosterone acetate-salt hypertensive rats
… NO plays a protective role opposing tone. Basal superoxide anion (02.-) production was increased in aortic rings from DOCA-salt hypertensive rats. Stretch increased 02.- production even further. Tempol, an 02.- scavenger, or apocynin, an inhibitor of NADPH-oxidase, attenuated hypertension. …
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Nitrogen oxide delivery systems for biological media
… the respective reactions of NO with oxygen and superoxide anion. Controlled delivery of these RNS at levels expected to occur in vivo is desirable in studying these processes and their role in the etiology of various diseases. Two delivery systems were developed that provide novel capabilities …
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The antioxidant properties of 4–quinolones compared to structurally related flavonoids
… 6-hydroxy-2-phenylquinolin-4(1 H)-one (8). The superoxide anion (NBT) assay demonstrated the ability of the compounds to scavenge superoxide anions, the first oxygen radical produced by the mitochondria, which is responsible for most of further oxygen radical production in the cell. The …
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