Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"supercharging"”.
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Supercharging Programming through Compiler Technology
The decline of Moore’s law and an increasing reliance on computation has led to an explosion of specialized software packages and hardware architectures. While this diversity enables unprecedented flexibility, it also requires domain-experts to learn how to customize programs to efficiently …
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Structural Comparison of Denatured and Supercharged Proteins in Gas and Solution Phases
… structure in the gas phase. Finally, protein supercharging helps to enhance mass spectrometry analysis by shifting charge state distributions towards a lower m/z range. By comparing a supercharged protein’s ATDs and CCS values, we can measure any influence supercharging has on protein …
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Supercharging: An Investigation into the Effects of External Amino Acid Residue Charge on the Solubility and Internal Electric Character of Bound Ligands in a Heme-Binding de novo-Designed Protein
… This work establishes the hard limits of supercharging within our experimental protein scaffold system, demonstrating that excessive positive charge increased the likelihood of amyloid plaque aggregation and excessive negative charge resulted in loss of the alpha-helix character essential …
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Development and Applications of Liquid Sample Desorption Electrospray Ionization Mass Spectrometry (DESI-MS)
… avoiding potential peak broadening. By spraying supercharging reagent, a specific compound to supercharge proteins, in the reactive DESI, protein eluent after LC can be supercharged. Interestingly, supercharging reagent can also reduce the notorious ion signal suppression effect caused by …
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Mechanistic Insights into Analyte Charge Enhancement using Mass Spectrometry and Molecular Dynamics Simulations
… more charge. In Chapter 3, we examined the supercharging effects of sulfolane on the ESI behavior of salt clusters using similar methods. Spiking NaI solutions with sulfolane resulted in the formation of highly charged cluster ions. MD simulations illustrate that sulfolane stabilizes the …
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The Mangrove Mosaic: An Ecological Landscape Design Strategy for Everglades City's Climate Adaptation and Phased Transition Amidst Sea-level Rise
… function. A key part of the project involves "supercharging" mangroves by restoring the coastal mangrove belt and using a combined double-breakwater and Thin-Layer Placement (TLP) method to capture and retain sediments. The thesis also examines adaptation pathways for residents by exploring how …