Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"super-specific methylation"”.
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Super-specific DNA methylation by a DNA methyltransferase coupled with a triple helix-forming oligonucleotide
… mammalian DNA MTases. It has been rendered a super-specific MTase by conjugation with a TFO designed to bind a triple helix-forming site (TFS) in the promoter of the epithelial cell adhesion molecule (EpCAM) with high specificity and affinity. This transmembrane glycoprotein is strongly …