Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"subviral Particles"”.
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Using the single-cycle flavivirus particle replivax to study flavivirus replication and immune response
… (WNV) that prevents the formation of infectious particles, unless the C gene is trans-complemented by a WNV C-expressing cell line. RepliVAX immunization results in a single round of infection, where the replication of genome leads to the production of subviral particles (SVP) and NS1 antigens …
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Cellular determinants of reovirus entry and infection
… method by which partially uncoated intermediate subviral particles (ISVPs) enter host cells remains unknown. Biochemical studies have suggested that ISVPs can directly penetrate the plasma membrane since these particles can cause membrane damage and hemolysis at high multiplicities of infection. …
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Characterization of single-cycle flavivirus particles for use as a vaccine to prevent West Nile disease and to examine immune responses to flavivirus infection
… and drives the production of highly antigenic subviral particles (SVPs) and NS1 without producing infectious virions. Thus, RepliVAX is expected to be highly potent yet exhibit a safety profile superior to traditional live-attenuated viral vaccines.\r\nHere we demonstrate that RepliVAX WN can …
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Einfluss posttranslationaler Modifikationen auf die Funktion des Prototyp Foamy Virus Hüllproteins
Die Familie der Retrovirinae wird in zwei Unterfamilien untergliedert, die Orthoretrovirinae und die Spumaretrovirinae. Foamyviren stellen aufgrund einiger besonderer Eigenschaften die einzigen Vertreter dieser Unterfamilie, die sie als Bindeglied zwischen den Retroviren und den Hepadnaviren …
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Determinanten und Mechanismen der foamyviralen Partikelfreisetzung
… von Kapsidlosen, Hüllprotein-haltigen subviralen Partikeln (SVP) fähig. Da eine Envunabhängige Freisetzung virus-ähnlicher Partikel durch ein FV Gag-Protein mit künstlichem Membrananker möglich ist, scheint das FV Gag-Protein auch essentielle strukturelle Elemente für die …