Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"subgenual"”.
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Marmoset emotional regulation during adolescence and adulthood, with a particular focus on risk-taking and the role of the subgenual anterior cingulate cortex in motivation and affective biases
… disorders, specifically mood disorders, is the subgenual anterior cingulate cortex (sgACC). Overactivation of sgACC in humans is observed in depression, and reducing neuronal activity in sgACC using deep brain stimulation alleviates depressive symptoms (Mayberg et al., 2005). However, the …
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Functional Connectivity of Reward Networks: Characterizing Mechanistic Underpinnings Involved in Positive Affect Deficits within Social Anxiety Disorder
… (ROIs)-couplings (i.e., OFC and insula, OFC and subgenual cingulate, insula and cingulate, and cingulate and subgenual cingulate) and diminished PA were present in individuals with SAD, but not controls. Lastly, results demonstrated that individuals with SAD had higher variability in their reward …
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Foundations for Improved Models of Value-Based Decision-Making: Neural Correlates in the Anterior Cingulate Cortex and their Implications
… the responses of neurons in the dorsal and subgenual anterior cingulate cortices (ACC) of rhesus macaques. Our findings in the dorsal anterior cingulate (dACC) are consistent with its direct involvement in the decision-making process. Moreover, neural responses to value in this region …
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The Dissociation of Valence and Intensity Using Alliesthesia and Thermal Stimulation
… included the medial orbitofrontal cortex, subgenual anterior cingulate cortex and amygdala, whereas stimulus intensity was correlated with activity in the insula, thalamus and striatum, among others. Our results suggest segregated patterns of neural activity underlying perceptions of …
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Optimizing Transcranial Focused Ultrasound: Calibration, Neuro Navigation, and BOLD fMRI Evidence of Neuromodulation
… to facilitate precise targeting of the right subgenual anterior cingulate cortex (right sgACC), enabling accurate placement of the ultrasound transducer based on individual anatomical data. Preliminary human trials were conducted with parameters chosen to balance efficacy and safety, adhering …
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Translational Neuroimaging of Emotion Processes in Posttraumatic Stress Disorder and Depression
… of the brain, the right anterior insula and the subgenual anterior cingulate cortex, exhibited pretreatment responses to negative emotional stimuli that were predictive of clinical response to treatment. Considered together, this work demonstrates the translational utility of neuroimaging of …
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Childhood Trauma And Emotion Processing Neurocircuitry
… including the amygdala, insula, and pregenual/subgenual anterior cingulate cortex (pgACC/sgACC). To examine the relevance of observed neurological changes, we evaluate behavioral performance on emotion processing neuropsychological tasks, as well as specific dimensions of subjective affective …
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Sex Differences in Risky Decision-Making Neural Processing and Its Link to Problematic Substance Use in Adolescents at Risk for Substance Use Disorders
… phase activation in the NAc in males and in the subgenual anterior cingulate cortex in females were associated with less problematic substance use. Conclusions: This dissertation highlights significant sex differences in both the neural processing of risky decision-making and its connection to …
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Cortical - Basal Ganglia Circuits: Control of Behaviour and Alcohol Misuse
… connectivity between limbic regions including subgenual anterior cingulate cortex, VS and STN. However, motor impulsivity, in the form of stopping ability, was associated with motoric regions including pre-SMA and STN. Compulsivity was captured as deficits in: reversal learning, implicating …
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Primate Ventromedial Prefrontal Cortex and the Physiological and Behavioural Dysfunction Characteristic of Mood and Anxiety Disorders
… within two key subregions of the vmPFC – the subgenual anterior cingulate cortex (sgACC, area 25) and perigenual anterior cingulate cortex (pgACC, area 32) – in discrete dimensions of behaviour and physiology affected in psychiatric disorders. Specifically, the impact of over-activity is …
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Recovery in Major Depressive Disorder: Neural and Clinical Perspectives
… application of resulting meta-analytic regions (subgenual and perigenual anterior cingulate cortex) in a confirmatory MDD sample. Although regions showed some predictive potential in the confirmatory sample, when predicting SSRI response, effects were inconsistent with prior studies, suggesting …
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Network-based approaches towards understanding the emergence of neurodevelopmental disorders
… analyses of bulk transcriptomic data from the subgenual anterior cingulate cortex (sgACC) of individuals with schizophrenia, bipolar disorder, major depressive disorder, and non-psychiatric controls. In Chapter 4, I apply weighted gene co-expression network analysis (WGCNA) to identify modules …