Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"subconjunctival"”.
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Development and Characterization of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers for Ocular Delivery via Subconjunctival Route: Synergistic Effect of Vitamin a Palmitate
… situ gel for improved ocular bioavailability by subconjunctival injection. FA, a corticosteroid administered for inhibiting the ocular inflammation either as intravitreal injection or as intravitreal implants. The FA-NLCs were developed by using vitamin A palmitate as one of the lipid components, …
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Development of an ocular drug release system for cattle
… with that of a field method of treatment using subconjunctival injections of Azimycin°ler demonstrated that the treatment using the ring device was significantly more effective than the subconjunctival injection method. Clinical observations showed that the eyes receiving the medicated ocular …
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The Use of Preclinical Models to Improve the Treatment of Retinoblastoma
… effective therapy in the clinic was the use of a subconjunctival administration. We thought if we could administer both drugs, one by systemic and one by a subconjunctival injection, perhaps we could decrease the systemic exposure with good tumor response. Detailed pharmacokinetic studies were …
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Bupivacaine liposomal injectable suspension (Nocita®) provides postoperative analgesia following eyelid injection in dogs undergoing enucleation
… and maintained with isoflurane. Dogs received a subconjunctival enucleation. Immediately prior to incision closure, the subcutaneous eyelid tissues were injected with BLIS or saline in a ring-block manner. All dogs received an oral 0.1 mg/kg dose of meloxicam at 8 hours postoperatively. Pain …
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Stenotrophomonas maltophilia induzierte Endophthalmitis
… and were treated with intravitreal, topical, subconjunctival and systemic antibiotics covering to the most likely pathogens. 2 days after surgery identification of S. maltophilia allowed change of therapy to trimethoprim/sulfamethoxazol (TMP-SMX) 960mg bid i.v. and Ciprofloxacin 400mg -750mg …
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Drug delivery strategies to overcome ocular hypertension
… hyaluronan-oxime hydrogel and injected into the subconjunctival space of the rat eye, the timolol palmitate CDA-hydrogel composite maintained an intraocular pressure-lowering effect for up to 49 days—far longer than the 6 hours achieved with conventional timolol maleate. This approach also …
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In vitro Sustained Release Delivery System for Hydrogen Sulfide Analogs
… of H2S in regulation of aqueous humor dynamics. Subconjunctival delivery can be the desired route since it targets both the anterior and the posterior segment. Some hydrogen sulfide donors are available which can produce H2S once they are inside our body but they must do so at sustained rate to …
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The Tumor Microenvironment Regulates Retinoblastoma Cell Survival
… as intra-ophthalmic artery, intravitreal, and subconjunctival administration. Still ocular salvage rates have not exceeded 70% in over two decades. Novel, safer therapies are required but there is a fundamental lack of knowledge about the biology of the tumor for the development of targeted …