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Showing 1 to 1 of 1 for “"structure-selective endonucleases (SSNs)"”.

  1. ATM plays multiple roles in crossover regulation during mouse spermatogenesis

    <p>During meiosis, each pair of homologous chromosomes must have at least one crossover recombination event, or they risk randomly segregating, leading to aneuploidy—a major cause of infertility, miscarriage, and birth defects. In humans, approximately 1 in 20 sperm and 1 in 4 oocytes are aneuploid …

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