Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"structure probing"”.
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Conformational features of the human U2-U6 snRNA complex
… we attempted to characterize the lowest energy structure of the complex in the absence of spliceosomal proteins using a combination of biophysical and biochemical techniques in the solution state. We first used enzymatic structure probing to evaluate the secondary structural fold of protein-free …
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Transcriptome-wide pseudouridine profiling reveals modification of critical E. coli mRNAs
… In Chapter 1, I provide an overview of the structure and function of pseudouridine, focusing on the properties that can impact the structure, translation, and interactome of the mRNAs that contain it. I give a brief review of the enzymes that carry out tRNA and rRNA modification, which are …