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Showing 1 to 20 of 43 for “"structure function studies"”.

  1. Structure/function studies of protein phosphatases

    Brenner, Rachel NatanyaMassachusetts Institute of Technology1995

    Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1995.

    mit Repository record

  2. Structure-function studies of bovine rhodopsin

    Kaushal, ShaleshMassachusetts Institute of Technology1994

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1994.

    mit Repository record

  3. Structure-Function Studies Of The Poliovirus Polymerase.

    Jablonski, Sandra A

    uab Repository record

  4. Structure-function studies of mammalian deoxycytidine kinases

    Elena Usova2003

    slu Repository record

  5. Structure-function studies of SLC15 peptide transporters

    Senan, AnishOxford Brookes University2015

    … and di- and tri- peptides and drugs similar in structure (peptidomimetics). PepT1, and to a lesser extent PepT2, have therefore gained attention due to their role in determining the absorption, retention and elimination of transported drugs. In this study three novel prodrug-carriers namely …

    oxford-brookes Repository record

  6. Structure-Function Studies on Two Phosphoenolpyruvate Carboxylases

    Dharmarajan, LakshmiVirginia Tech2010

    … and C₄ plants via Rubisco. We are studying the structure-function aspects of both enzymes, with a goal of discovering new elements in these enzymes which can modulate catalysis. We have undertaken an interdisciplinary approach for this work and have shown that a combination of experimental and …

    vt Repository record

  7. STRUCTURE-FUNCTION STUDIES OF NOVEL MEDICALLY RELEVANT FLAVOENZYMES

    D. ZucchiniUniversità degli Studi di Milano2010

    … has been shown to be essential for MICAL function, but its catalytic activity has not been defined yet. At variance with PHBH, MICAL-MO exhibits a detectable NADPH oxidase activity. The rate of the overall reaction is fully determined by that of enzyme reduction by NADPH, which takes place …

    milano Repository record

  8. Structure-function studies of native and recombinant transferrins

    Sargent, Peter Joseph2006

    kings Repository record

  9. Structure-Function Studies of a Truncated Ice-Nucleation Protein

    Andrin, Evan J. C.2015

    … subzero temperatures. Despite having an opposite function to antifreeze proteins (AFPs), INPs and AFPs both have significant similarities in sequence and structure. Based on these common features, I hypothesize that INPs also organize water molecules on their surface into ice-like geometries, as …

    queens Repository record

  10. Structure-function studies of human SLC36 amino acid transporters

    Pillai, Samyuktha MuralidharanOxford Brookes University2011

    … (hPATs).This is due to hPATs 1 and 2 having been functionally characterized as proton coupled transporters that bring about a 1:1 symport of H+ and an amino acid across the membrane (with optimum uptake at an extracellular pH of 5.5). Their main substrates were found to be the small neutral amino …

    oxford-brookes Repository record

  11. Structure-function studies of the Parkinsonism-linked protein DJ-1

    Puno, M.R.A.University of Westminster2014

    DJ-1 is a multifunctional protein linked to familial Parkinson’s disease. DJ-1 has been suggested to exert its cytoprotective function, in part, by acting as a copper carrier that can sequester the reactive metal and/or provide the copper cofactor for the activation of the Cu-Zn superoxide …

    westminster Repository record

  12. STRUCTURE-FUNCTION STUDIES OF TRANSLOCATED EFFECTORS FROM THE LATE BLIGHT PATHOGEN

    King, StuartUniversity of East Anglia2013

    … basis of disease. Determining the adaptive functions of effectors might reveal previously unexploited management strategies. This work details structure-function studies of two translocated effectors from the late blight pathogen; PexRD2, a representative RXLR effector, and CRN8, an effector …

    east-anglia Repository record

  13. Structure/Function Studies on Vps9 domain-containing Ankyrin Repeat protein (VARP)

    Crawley-Snowdon, HarrietUniversity of Cambridge2019

    … interaction with Vps29. The Varp:Vps29 complex structure was determined by a combined X-Ray Crystallographic/NMR method. This thesis demonstrates that one zinc knuckle sequence of Varp is sufficient to form an interaction with Vps29, with an affinity in the micromolar range. Single point …

    cambridge Repository record

  14. STRUCTURE-FUNCTION STUDIES OF MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASES FROM GUT COMMENSAL BACTERIA

    Li, ArthurUniversity of East Anglia2014

    … In this study, high resolution X-ray crystal structures of Minpps from two human commensal gut bacteria, Bacteroides thetaiotaomicron (BtMinpp) and Bifidobacterium longum (BlMinpp), were solved and refined. High performance liquid chromatography was employed to analyse the products of InsP6 …

    east-anglia Repository record

  15. Discovery of a Novel Metalloregular Family: Structure/Function Studies of E. Coli Rcnr

    Iwig, Jeffrey2010

    … and protein translation. Despite these essential functions, excess metal ions can lead to cell death through the generation of oxidative damage or the occupation of non-native metal sites. Acquiring metal ions from the environment while limiting possible toxic effects requires the coordinated …

    wustl Repository record

  16. Modification of bovine beta-casein using genetic engineering and its structure/function studies

    Choi, Byung-KwonUniversity of Illinois at Urbana-Champaign2011

    Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:55:53Z Item is restricted indefinitely.

    uiuc Repository record

  17. Structure-function studies of respiratory complex I from Paracoccus denitrificans using membrane mimetics

    Ivanov, BozhidarUniversity of Cambridge2023

    … system for studying its mechanism. However, the structure of the enzyme remains unknown, due to its intrinsically flexible and fragile nature, restricting the power of the system to tackle specific mechanistic questions on the molecular level. This study employs a multifaceted approach to develop …

    cambridge Repository record

  18. Structure-Function Studies on Human Epithelial Cystic Fibrosis Chloride Channels Expressed in Xenopus Laevis Oocytes

    Csanady, Laszlo

    … split channels 1-633 plus 837-1480 were functionally similar to 1-835 plus 837-1480, including enhanced apparent ATP affinity and less tight binding of AMPPNP, but were more active before phosphorylation. Intriguingly, 1-633 plus 837-1480 channels, lacking the R domain, were still …

    rockefeller Repository record

  19. Structure-Function Studies of CorA-Mrs2-Alr1 Superfamily of Magnesium Channels: Bacterial CorA and Yeast Alr1

    Kruglyak, Natalya2018

    … This thesis details the investigation of the structure-function relationship of the bacterial CorA and yeast Alr1 using biophysical, biochemical and bioinformatic approaches. Members of the CorA-Mrs2-Alr1 superfamily contain a canonical GMN motif located at the entrance to the ion …

    toronto-retro Repository record

  20. PLP-Dependent α-Oxoamine Synthases: Phylogenetic Analysis, Structural Plasticity, and Structure-Function Studies on 5-Aminolevulinate Synthase

    Turbeville, Tracy DDigital Commons @ University of South Florida2009

    … plasticity of ALAS has been documented in studies of functional circularly permuted ALAS variants and the single polypeptide chain ALAS dimer (ALAS/ALAS) exhibiting a greater turnover number than wild-type ALAS. An examination of the contribution of each ALAS/ALAS active site to the …

    usf Repository record

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