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Showing 1 to 3 of 3 for “"structural variation (SV)"”.

  1. Genic copy number variation associated with abiotic/biotic stress among a set of progenitors of contemporary maize germplasm

    … as a model genetic organism. Although sequence variation is most commonly associated with single nucleotide polymorphisms, it is estimated that a greater portion of the genome is affected by structural variation (SV). This is a broad phenomenon that includes copy number variation (CNV), …

    uiuc Repository record for Genic copy number variation associated with abiotic/biotic stress among a set of progenitors of contemporary maize germplasm (opens in a new tab)

  2. A novel genomics and bioinformatics approach to assess immunoglobulin and T cell receptor rearrangements and somatic hypermutation in lymphoproliferative disorders

    … high sample throughput and investigation of structural variation (SV) and mutation analysis.<br/><br/>Several NGS applications have been proposed for clonality and SHM status reporting but these still rely on initial PCR amplification of clonal sequences, limiting analysis of other molecular …

    qu-belfast Repository record for A novel genomics and bioinformatics approach to assess immunoglobulin and T cell receptor rearrangements and somatic hypermutation in lymphoproliferative disorders (opens in a new tab)

  3. Bayesian Integration and Modeling for Next-generation Sequencing Data Analysis

    … Focused on a specific type of genome mutation, structural variation (SV), we develop a novel pattern-based probabilistic approach, namely PSSV, to identify somatic SVs from whole genome sequencing (WGS) data. PSSV features a mixture model with hidden states representing different mutation …

    vt Repository record for Bayesian Integration and Modeling for Next-generation Sequencing Data Analysis (opens in a new tab)