Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"structural vaccinology"”.
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MOLECULAR DYNAMICS SIMULATIONS OF BIOLOGICAL MACROMOLECULES: APPLICATIONS TO STRUCTURAL VACCINOLOGY AND PEPTIDE DESIGN
… studies of proteins have shown that sequence and structural similarities alone may not be sufficient for reliable prediction of their interaction properties. This is particularly true for proteins recognizing specific antibodies, where the prediction of antibody-binding sites, called epitopes, has …
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The rational structure-based design of a protein nanoparticle presenting a chimeric MenB antigen
… vaccine immunogenicity.;In addition, advances in structural and computational biology have enabled a new era of vaccine design and discovery, Structural Vaccinology, which seeks the rational structure-based design of improved vaccine antigens measured in terms of epitope presentation, stability …
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Computational Evaluation and Structure-based Design for Potentiation of Nicotine Vaccines
Existing therapeutic options for the alleviation of nicotine addiction have been largely ineffective at stemming the tide of tobacco use. Immunopharmacotherapy, or vaccination, is a promising, alternate therapy that is currently being explored. Results from previous studies indicate that nicotine …