Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"structural genomics"”.
-
High-throughput evaluation of protein folding conditions and expression constructs for structural genomics
Das E. coli Expressionssystem ist das am häufigsten angewandte hinsichtlich der rekombinante Proteinexpression für strukturelle und funktionelle Analysen aufgrund der hohen erzielten Ausbeuten und der einfachen Handhabbarkeit. Allerdings ist insbesondere die Expression eukaryotischer Proteine in E. …
-
Structural studies of putative general stress and related proteins from Deinococcus radiodurans
… of ionising radiation has formed the basis of a structural genomics project underway at the European Synchrotron Radiation Facility (ESRF), Grenoble, France. The work presented in this study forms part of the ESRF’s D. radiodurans initiative, and was funded by the Biotechnology and Biological …
-
A study of intrinsic disorder and its role in functional proteomics
… have the potential to impact ongoing structural genomics initiatives by suggesting alternative methods for determining structure for targets containing regions of disorder. Additional ramifications of results from this work include directing attention towards the possible use of …
-
Novel Algorithms for Automated NMR Assignment and Protein Structure Determination
… (NMR) spectroscopy plays an important role in structural genomics. Unfortunately, current NMR structure determination is still limited by the lengthy time required to process and analyze the experimental data. A major bottleneck in protein structure determination via NMR is the interpretation …
-
Expression and characterisation of metalloproteins from mycobacterium tuberculosis
… strain of Mycobacterium tuberculosis. Subsequent structural genomics projects have identified hundreds of potential targets for structure-based drug design. The research presented in this thesis focuses on the expression and characterisation of targets from the Mycobacterium tuberculosis genome. …