Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"stress-induced premature senescence"”.
-
The Effect of Stress Induced Premature Senescence on the Expression of Heterogeneous RibonucleoIeoprotein
… nuclear ribonucleoproteins (hnRNP) in cellular senescence is yet to be defined. Cellular senescence is a terminal growth arrest in somatic cells. It is thought to be the consequence of telomeric shortening that acts as a DNA damage signal. Conversely, cells induced into premature senescence …
-
Understanding the Effect Of 1,3-Butadiene on Human Lung Fibroblasts: Does Exposure to 1,3-Butadiene Induce Senescence?
Cellular senescence is a state of irreversible growth arrest induced by either telomere shortening (replicative senescence) or telomere-independent signals (stress-induced premature senescence or SIPS). Recent studies have shown that cigarette smoke extract induces senescence in lung fibroblasts …
-
Regulatio of actin cytoskeleton by TIS21 vi downregulating reactive oxygen species (ROS) in the doxorubicin-induced premature senescenc
… differentiation and apoptosis. Cellular senescence is an irreversible arrest of proliferation, which is induced by replicative cell division (replicative senescence) or stress (stress induced premature senescence; SIPS). Cellular senescence is induced by DNA damage, telomere shortening or …
-
Pre-clinical evaluation of lethal and sublethal DNA damage in human cell cultures by ultrashort pulse and ultra-high dose rate laser accelerated protons
… endpoints: DNA DSB damage, cell survival and Stress-Induced Premature Senescence (SIPS) in human skin fibroblasts (AG01522) and endothelial cells (HUVEC). Experiments with these beams have been performed in several laser facilities based in the UK (TARANIS, VULCAN) and France (LULI), and …
-
Ion dosimetry for radiobiology experiments employing laser-accelerated beams
… 2 hours post-irradiation) appears similar. A stress-induced premature senescence (SIPS) investigation also revealed that laser-driven protons appear to be more effective in inducing premature senescence than x-rays in HUVEC cell lines. Although not all biological data is currently available …