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Showing 1 to 3 of 3 for “"stress granules (SG)"”.

  1. Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance

    … and potential as therapeutic targets in disease. Stress granules (SG) are membrane-less ribonucleoprotein condensates that form in response to various stress stimuli via phase separation. SG act as a protective mechanism to cope with acute stress, but persistent SG have cytotoxic effects that are …

    utswmed Repository record for Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance (opens in a new tab)

  2. Sam68, Stress Granules, and translational control of HIV-1 nef mRNA

    … to form a macromolecular structure called stress granules (SG). In addition, we demonstrated that these variants bound to nef mRNA in a sequence-specific manner. Furthermore, we showed that these variants co-localized with nef mRNA in SG. Importantly, we validated these findings in the …

    iupui Repository record for Sam68, Stress Granules, and translational control of HIV-1 nef mRNA (opens in a new tab)

  3. Cellular responses to external threats probed by super-resolution microscopy

    … granular aggregates called as antiviral granules (AVGs). We infected/transfected cells by influenza virus lacking NS1 (IAVΔNS1) or polyinosinic:polycytidylic acid (poly I:C) to induce AVGs. We found in AVGs, RIG-I forms clusters of around 110nm in diameter. Then we treated intact cells …

    uiuc Repository record for Cellular responses to external threats probed by super-resolution microscopy (opens in a new tab)