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Showing 1 to 4 of 4 for “"strangles"”.
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Investigations Into a Rationally Designed Modified Live Vaccine for Equine Strangles
Equine strangles is an ancient disease of horses that continues to be a major problem in the modern era. Strangles has many properties of a disease that could be controlled or even eradicated. The agent of strangles Streptococcus equi ssp. equi has a very narrow host range, infecting Equidae almost …
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The Chondroid Conundrum: Transpharyngeal Removal of Guttural Pouch Chondroids in Horses
Strangles is an extremely infectious disease of horses that has negative financial and health consequences. After infection, some horses form balls of concrete-like pus in a structure in an air-filled sac of the ear canal called guttural pouches (GPs). These concretions, called chondroids, allow …
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Comparative and Functional Genomic Analysis of <i>Streptococcus Equi</i> and <i>Streptococcus Zooepidemicus</i> : Identifying Novel Vaccine Targets
… pathogen of horses and the aetiological agent of strangles. Available evidence suggests that <i>S. equi</i> evolved from <i>Streptococcus equi</i> subspecies <i>zooepidemicus</i> (<i>S. zooepidemicus</i>), a versatile bacterium that is often isolated from the equine respiratory tract, but can …
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Barcoded Transposon Directed Insertion-site Sequencing (TraDIS); a tool to improve our understanding of the functional genomics of Streptococcus equi subsp. equi
Strangles, caused by Streptococcus equi (S. equi) remains the most frequently diagnosed infectious disease of horses and is a cause of significant welfare and economic cost. Vaccine research has been limited by the time taken to make mutations in individual genes to determine their role in the …