Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"strain differences"”.
-
Exploring Nipah virus strain differences through use of recombinant and chimeric viruses as well as utilization of a novel 3D human lung model
… Despite high sequence homology between the strains, there are several key differences in epidemiological and pathobiological features. The reasons for these differences have not been thoroughly investigated and this dissertation seeks to address this gap. In addition to constructing a …
-
Sublethal vapor-induced responses of the German cockroach to commercial pesticide formulations
… recorded during a two hour period from different strains that had been allowed to acclimate to a harborage. The dispersal response of large nymphs from a pesticide susceptible laboratory strain (VPI) was compared to two propoxur resistant field strains (Carver, Kenly) after exposure to four …
-
Seizure development in kindling fast and kindling slow rat strains
… kindling stimulation in two selectively bred rat strains. In the present study, kindling FAST and kindling SLOW rat strains were shown to exhibit differences in the development and subsequent manifestation of amygdala kindled seizures. SLOW animals required far more stimulations than FAST animals …
-
Studies on the regulation of solvent production and endospore formation in Clostridium Acetobutylicum P262
… formation in Clostridium acetobutylicum strain P262. Growth and endospore formation was monitored in a number of complex and minimal media and as a result of these studies a new defined sporulation medium was developed. The defined system produced high levels of solvents and supported 60 …
-
A Behavioral and Anatomical Analysis of Conditioned Taste Aversion in C57BL/6J and DBA/2J Mice
… a specified behavior. </p> <p>The use of inbred strains of mice, specifically the common strains C57BL/6J (B6) and DBA/2J (D2), allows for the investigation of phenotypic variation and specific genes underlying the various components of CTA. B6 and D2 mice have previously been characterized in …
-
Clostridium difficile: expression of virulence factors, resistance to disinfectants and interactions with human cells
… the emergence and decline of different strains of varying virulence and a broad spectrum of disease from asymptomatic carriage and mild infection to severe pseudomembranous colitis have been observed. The main aim of this three-part thesis was to identify bacterial factors that might …
-
Effects of light and temperature on the formation of sexual structures in the family Saprolegniaceae
… formed sexual structures during the experiments. Differences in light reactions and growth rates of these two isolates indicated physiological strain differences. Photoreactivation was demonstrated in S. ferax and both isolates of S. parasitica. Evidence was shown that light caused production of …
-
Modulation of host NF-[k̳̳a̳p̳p̳a̳]B pathway by the Toxoplasma gondii secreted factor, GRA15
… GRA 15 may complex with TRAF3. Some Toxoplasma strains activate the host NF-[kappa]B pathway much more than others. A combination of factors, including differences in expression and sequence of GRA 15, as well as other inhibitory parasite factors are responsible for conferring these strain …
-
Defining the tropism of Listeria monocytogenes using a comparative genomics approach
… infections. Ubiquitous in the environment, strains are often classified into lineages I (serovars 1/2a, 1/2c, 3a; food); II (containing serovars 1/2b, 4b, 3b; human illness); and III (4a, 4c; food-production). It is not clearly understood how serovars become tropic to a particular niche. The …
-
Determinants of cns adult neurogenesis are sex, hormones, mouse strain, age, and brain region
… With a short 2 h BrdU pulse, no gender and strain differences are present at 6-8wk. At 6-8mo, the number of BrdU+ cells decreases 2-fold in both sexes, strains and regions indicating a common aging mechanism regulates BrdU incorporation. Strikingly, 2X more BrdU+ cells are found in all brain …
-
The Effect of Embryonic Alcohol Exposure on Brain Function and Behavior in Zebrafish Strains
… function and behavior in different zebrafish strains? My first experiment explored the influence of environmental factors salinity and olfactory cues on zebrafish behavior. This was conducted to reduce experimental error variation and create more sensitive behavioral paradigms. My second …
-
Light-At-Night and Mood: Examining The Role Of Sex In C57Bl/6 Mice
… behaviours and that there would be sex-specific differences. Animals were either singly or group housed for a three week period where locomotor activity was measured. After this period they were tested on a range of tests of emotional behaviours. Animals were subsequently placed into either 12 h …
-
Some Aspects of the Colonisation and Decay of Fungicidally-Protected Cotton Textiles by Soil Fungi
… special mention being made of effects of pH and strain differences on Trichoderma viride. Results of respirometric investigations into the effects of low levels of PCPL-based fungicides on soil organisms are set out and discussed. Details are given of the development and employment of a simple …
-
The competitive dynamics of toxic and non-toxic ribotypes of the harmful dinoflagellate Alexandrium tamarense in Scottish waters
… first time, Group I and Group III A. tamarense strains to be studied in co-culture. In isolation, toxin<br/>production of the Group I strain was elevated under P limitation as well as at low temperature and short light (spring) conditions. In co-culture a competitive interaction between Group I …
-
Bone Properties of Recombinant Inbred Line - BXD Mouse
… bone structural response.</p> <p>51 BXD RI mouse strains were analyzed, including progenitor C57BL/6J (n=16) and DBA/2J (n=15), and two first filial generations (D2B6F1 and B6D2F1). Bones were collected from 10 to 14-week old females and males (N≥3 each group) and bone parameters were measured at …
-
Heritability of Nociception and Antinociception in the Laboratory Mouse
… measures among a common set of inbred mouse strains, revealing the existence of five fundamental ""types"" of nociception: (1) baseline thermal; (2) spontaneous responses to noxious chemical stimuli; (3) thermal hyperalgesia; (4) mechanical allodynia; and (5) afferent input-dependent …
-
Structural Elucidation of [RNQ+] prions Transmissible Infectivity
… to what is observed with mammalian prions strains, is observed within yeast also. To decipher how structural differences between infectious and non-infectious amyloid form, we formulated the hypothesis that structural differences in Rnq1 prion formation account for drastic changes within …
-
Evasion of interferon-gamma responses by Toxoplasma gondii in murine and human fibroblasts
… animals, and genetically diverse Toxoplasma strains may be adapted to specific hosts. Toxoplasma must evade host immunity without killing the host to establish a chronic infection and ensure transmission. Interferon-gamma (IFNγ) activation of non-immune cells is crucial for host defense …
-
Reziproke Transplantat-Wirt Interaktionen von dopaminergen Neuronen im Tiermodell der Parkinsonschen Krankheit
Das Konzept der intracerebralen Transplantation fetaler dopaminerger Zellen bei der Parkinsonschen Erkrankung zeigt sowohl in klinischen Untersuchungen als auch im tierexperimentellen Ansatz noch deutliche Defizite in der funktionell restaurativen Kapazität der Transplantate. Als mögliche Gründe …
Page 1 of 2