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Showing 1 to 20 of 24 for “"stone formation"”.
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The Effects of Various Therapeutics on Cystine Stone Formation
… tiopronin on its ability to inhibit and prevent stone formation and found it to be only moderately effective. In addition to observing tiopronin as a therapeutic, we also looked into the effects of potassium citrate as a treatment. We found potassium citrate to have a varying effects on both …
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The effect of Ascorbic acid ingestion on the risk of calcium oxalate kidney stone formation
… acid on the risk of calcium oxalate kidney stone formation. Ten healthy male subjects (ages 20 to 30 years) participated in the study. Each was required to ingest a daily dose of 4 g ascorbic acid per day for a period of 5 days. Twenty-four hour urines were collected at various times prior …
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The effects of calcium, magnesium and citrate health supplements on urinary risk factors for calcium oxalate kidney stone formation
… on the risk of calcium oxalate (CaOx) kidney stone formation. Four separate studies comprised the entire project. In the first study, a new approach was implemented to investigate the individual, additive and synergistic effects of calcium, magnesium and citrate health supplements on the …
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The effects of calcium, magnesium and citrate health supplements on urinary risk factors for calcium oxalate kidney stone formation
… on the risk of calcium oxalate (CaOx) kidney stone formation. Four separate studies comprised the entire project. In the first study, a new approach was implemented to investigate the individual, additive and synergistic effects of calcium, magnesium and citrate health supplements on the …
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Investigation of the effect of hydroxycitric acid on urinary calcium oxalate risk factors for kidney stone formation in artificial urine: theoretical modelling and in vitro crystallisation experiments
… or urolithiasis, commonly known as kidney stones, is a common medical problem. Kidney stones are composed of different mineral types. Calcium Oxalate is the most common kind of stone. The principal aim of this research was to establish whether hydroxycitrate (HCA) affects and/or inhibits …
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Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation
… world are likely to suffer at least one kidney stone in their life. The incidence of kidney stone disease in South Africa is similar in white males; however stone occurrence in the South African black population is extremely rare. The difference between the incidences of kidney stones in the …
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Investigation of the role of dietary myo-inositol hexakisphosphate (phytate) on the relative risk of calcium oxalate kidney stone formation in black and white male South African subjects
… studies have shown that caJclum oxalate (CaOx) stone-formers have lower urinary concentrations of myo-inositol hexakisphosphate (phytate or IPe) than healthy individuals, that dietary intake of this substance leads to its increased urinary excretion and that it is an inhibitor of CaOx nucleation …
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Modeling Uric Acid Kidney Stones Disease in D. melanogaster using RNAi and Dietary Modulation
… predictor for gout and forming uric acid kidney stones is elevated uric acid in the serum and urine respectively. It is known that uric acid is an end metabolite of purine degradation in humans, but in other species from <em>D. melanogaster </em>to lower apes,<em> </em>uric acid can be further …
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Investigation of the potential beneficial effects of supplemental polyunsaturated fatty acids and glycosaminoglycans on the risk factors for calcium oxalate kidney stone formation using theoretical, experimental and human models
… with regard to calcium oxalate (CaOx) renal stone formation were tested in this thesis. The first hypothesis is that fatty acid (FA) supplementation (n-6 and n-3) and chondroitin sulphate (CS) supplementation may reduce the plasma (FA) and urinary (FA and CS) risk factors for CaOx renal stone …
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Crystalluria in various groups of sportsmen
… whether they are at risk with regard to kidney stone formation. Particle size distribution analysis (Coulter counter), ultra-structural analyses (SEM) and urine analysis were conducted. The background to various factors relating to stone formation is discussed as well as the general theory …
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Avian Infectious Bronchitis Virus: A Tropism for the Rooster Reproductive Tract and Effects on Reproductive Performance
… dysfunction of the epididymal region, epididymal stones, has been shown to affect fertility in the rooster. The cause of these epididymal stones was investigated and avian infectious bronchitis virus (AIBV) has been identified as a cause. AIBV is a highly contagious respiratory disease in …
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Investigating Potential Therapies to Decrease the Rate of Cystine Stone Growth in Slc3a1-/- Mice
… of cystine in the urine, resulting in cystine stones. The SLC3A1/SLC7A9 cystine transporter accounts for 90% of cystine reabsorption and mutations in this transporter result in the formation of cystine stones. For this study, micro-computed tomography (µCT) scanning was evaluated for its …
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Physical, chemical and biological controls on the origin, crystallization and dissolution of human kidney stones
Kidney stones are mineral deposits in the renal system that afflict 1 in 11 people worldwide and the incidence and prevalence is increasing globally. Over 70% of stones are composed of calcium oxalate and other mineralogies include struvite, brushite, and apatite. Currently, stones are thought to …
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Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans
Stone incidence in South African blacks is extremely rare. The hypothesis to be tested is whether this apparent immunity can be attributed to the presence of more potent inhibitors of calcium oxalate (CaOx) crystallisation in urine from blacks compared to those occurring in the urine of white …
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Evaluating oxalate-degrading Lactobacillus spp. for their ability to be used as probiotics in the treatment of kidney stone disease
Although the direct cause of kidney stone formation is not known, reports have suggested it is probably a multifactorial disease. Lactobacillus strains which potentially had increased ability to degrade oxalate were previously isolated from a healthy low kidney stone risk group. The aim of this …
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Rarity of kidney stones in South Africa's black population : studies of urinary macromolecules, crystal matrix extract containing osteopontin, and bone turnover markers in urine and serum from black and white subjects as a key to understanding this paradox
… contributing towards the rarity of kidney stone disease in the South African black population. Healthy, age-matched male subjects from the black and white population groups were recruited for this purpose. In several of the studies, subjects followed a standardized diet and were required to …
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Mutationsspektrum in den Genen SLC3A1 und SLC7A9 bei jugendlichen Cystinuriepatienten
Cystinuria is a hereditary kidney stone disease which is caused by a renal tubular defect of reabsorption of cystine and the dibasic amino acids lysine, arginine and ornithine. Once the threshold of solubility is exceeded cystine precipitates and subsequently patients suffer from recurrent kidney …
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Η ΣΥΜΒΟΛΗ ΤΗΣ ΚΑΛΛΙΕΡΓΕΙΑΣ ΤΩΝ ΧΕΙΡΟΥΡΓΙΚΩΣ ΑΦΑΙΡΕΘΕΝΤΩΝ ΛΙΘΩΝ ΤΟΥ ΑΝΩΤΕΡΟΥ ΟΥΡΟΠΟΙΗΤΙΚΟΥ ΣΥΣΤΗΜΑΤΟΣ ΣΤΗΝ ΑΝΤΙΜΕΤΩΠΙΣΗ ΤΗΣ ΦΛΕΓΜΟΝΩΔΟΥΣ ΛΙΘΙΑΣΕΩΣ
… INFECTION RENAL CALCULI OR SO-CALLED STRUVITE STONES AND URINARY TRACT INFECTION WITH UREASE PRODUCING MICRO-ORGANISMS IS WELL DOCUMENTED. THE LITHOGENIC MECHANISM OF INFECTION INDUCED STONES HIGHLIGHTS THE NEED TO IDENTIFY THE INFECTIVE OR NOT NATURE OF URINARY STONES IN ORDER TO PLAN THE …
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Ionic processes in urine: a study of factors which may affect the renal excretion of inorganic phosphate
… investigations into the aetiology of renal stone formation were commenced in this laboratory, so creating an opportunity for the study of the physico-chemical structure of urine. As such a study was also clearly desirable preliminary to the further investigation of possible physico-chemical …
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Thick target pixe analysis
… of small traces of metals in human kidney stones and for the study of interrelationships between trace element concentrations with time of stone formation, in stones excreted from a single patient.
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