Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"stimuli-sensitive"”.
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Multilayer capsules with stimuli-sensitive properties : pH-response and carbohydrate-sensing
Polyelectrolyte microcapsules containing stimuli-responsive polymers have potential applications in the fields of sensors or actuators, stimulable microcontainers and controlled drug delivery. Such capsules were prepared, with the focus on pH-sensitivity and carbohydrate-sensing. First, …
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The synthesis of well-defined functional homo- and block copolymers in aqueous media via Reversible Addition-Fragmentation Chain Transfer (RAFT) Polymerization
… with complex structure, such as amphiphilic and stimuli-sensitive block copolymers. These include polymers containing one or even two stimuli-sensitive hydrophilic blocks. The hydrophilic character of a single or of several blocks was switched by changing the pH, the temperature or the salt …
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Synthesis and characterization of stimuli-responsive microgels based on poly(glycidol)block copolymers
… in ATRP of NIPAM and 4VP to give well-defined stimuli sensitive block copolymers of targeted molar ratio of blocks. The results obtained from light scattering methods showed formation of stable aggregates upon stimuli (pH or temperature) by all the obtained polymers. Additionally, …
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Design of PolyMOCs and the synthesis of crosslinkers for the BASP platform
… varying anchor groups and crosslinkers that are stimuli-sensitive for the brush-arm star polymer (BASP) drug delivery platform. Variation of MM anchor groups modifies the rate of propagation of ring-opening metastasis polymerization (ROMP), while the design of crosslinkers that are acid- and …
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Synthetic Materials with Redox-Triggers for Imaging and Drug Delivery
<p>Synthetic materials embedded with stimuli-responsive cleavable bonds have been extensively utilized for the development of site-targeted drug delivery system and selective imaging reporters. We developed stimuli-sensitive materials with two different redox switches including trimethyl-locked …
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Thermo-activated drug release.
… diseases. Development of a respirable, stimuli-responsive aerosol formulation would further enhance the drug delivery efficiency. In this thesis, it is postulated that a magnetite/lipid formulation stimulated by alternating magnetic fields can be adapted for use as a thermal-activated …
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New inverse opal hydrogels as platform for detecting macromolecules
… These sensor devices are based on the sensitivemodulation of the visual band gap of a photonic crystal (PhC), which is induced by the selective binding of analytes, triggering a volume phase transition. The PhCs introduced by this work show a high sensitivity not only for small …
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Modeling interactions between cells and the aqueous environment
… loosing their shape. A number of hydrogels are stimuli-sensitive. They can change their structures and properties in response to changes in environment, such as pH, temperature, and ionic strength. These polymer hydrogels have wide applications in various biological and clinical fields, …
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Design of functional polymeric materials for cancer-targeted drug delivery and cellular capture and isolation
… (MMP-2) enzyme for the design and synthesis of stimuli-sensitive synthetic block copolymer polymeric micelles (BCPMs) by reversible addition-fragmentation chain transfer (RAFT) polymerization for targeted delivery of therapeutics to cancer cells. The synthesized BCPMs were extensively studied …
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Photo-crosslinked Surface Attached Thin Hydrogel Layers
Stimuli sensitive polymers and hydrogels respond with large property changes to small physical and chemical stimuli (e.g. temperature, pH, ionic strength). The bulk behavior of these polymers is widely studied and they show an isotropic swelling. However, thin hydrogel layers of polymers on a …
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Entwicklung multi-stimuli sensitiver Materialien auf der Basis von flüssigkristallinen Elastomeren
… Funktion erzielt werden kann. Daher wurden multi-stimuli sensitive Materialien entwickelt die eine Kopplung des Formänderungs- und des Formgedächtniseffektes aufweisen. Dazu wurden zwei Konzepte entwickelt, die sich hinsichtlich der Reihenfolge der verwendeten Stimuli unterscheiden. Im ersten …
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Formulation of Hyaluronidase Enzyme Sensitive Topical Nanomicrobicides for HIV Virus Transmission Prevention
… study was designed to test the hypothesis that a stimuli-sensitive, safe and mucoadhesive thiolated hyaluronic acid (HA) based nanofibers (NFs) loaded with a topical vaginal microbicide (TFV) can be used for the prevention of HIV virus vaginal transmission in women. To test this, a novel thiolated …