Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"steroid metabolism"”.
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The Role of 5-Alpha Reductase 3 In Steroid Metabolism
… novel member of the 5-alpha reductase family, in steroid metabolism and prostate carcinogenesis.</p> <p><strong>Materials and Methods</strong></p> <p>HEK293 cells were transfected with the SRD5A3 human cDNA ORF Clone from<strong> </strong>OriGene. Steroid substrates (testosterone, progesterone, …
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Steroid metabolism in the human gut by microbial hydroxysteroid dehydrogenases
Bile acids and cortisol are steroid hormones derived from cholesterol that are important signaling molecules in the human body. Bile acids are essential for nutrient solubilization and absorption in the gut while cortisol is involved in stress response and metabolism throughout the body. The gut …
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The Possible Role of Extra-Gonadal Metabolism of Steroids in The Regulation of Plasma Steroid Levels (Cytochrome P-450, Liver)
The circulating level of steroid hormones is determined by both the rate of production by the steroidogenic tissue and by the rate of elimination from the circulation. The rate of metabolism of steroid hormones to more water soluble compounds can be influenced by a variety of factors including diet …
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Molecular pathogenesis of Helicobacter hepaticus induced liver disease
… to peroxisome proliferator, cholesterol, and steroid metabolism pathways. Transcriptional profiling of hepatic genes documented gene expression signatures in the livers of H. hepaticus infected male A/JCr mice with chronic progressive hepatitis and preneoplastic liver lesions, complemented the …
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Uncovering functional mechanisms in cancer through integrative genomics
The genome has been called the blueprint of life for it encodes a complete set of genetic instructions that specify the precise design and timing of functional molecules (such as RNAs and proteins) responsible for carrying out all cellular processes. In recent years, the human genome, comprised of …
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MATERNAL DETERMINANTS OF OOCYTE AND EMBRYO QUALITY
… types of oocytes. These mRNAs are involved in steroid metabolism, cell-cell interactions, cellular homeostasis, cell adhesion, mRNA stability and translation. In addition, the overexpression of several imprinted genes in IVM oocytes were detected, indicating a possible loss of correct …
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Dietary tomato carotenoids and β-carotene-15,15'- dioxygenase (Bco1) genotype alter androgen metabolism, lipid metabolism, and prostate cancer progression in mice
… effects of Bco1 loss on lipid and cholesterol metabolism in vivo have occasionally been described, few investigators have reported extensively on this. Furthermore, given the intersections of lipid metabolism, cholesterol/steroid metabolism, and carotenoid transport and distribution, functions …