Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"steroid biosynthesis"”.
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Biosynthesis and Signaling of Glucocorticoids and Progestins and Their Effects on Myelin Synthesis in Schwann Cell/neuronal Co-Cultures
… nerve impulses in a fast and efficient manner. Steroids hormones can be synthesized de novo in the nervous system. The major objective of this research was to identify the steroid signal transduction pathways between neurons and Schwann cells that regulate the steps in myelin formation. Schwann …
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The Regulation and Mechanism of Myelin Synthesis Involving Endogenous Steroid Hormones
… as a novel neuronal signal that may regulate steroid biosynthesis in Schwann cells and ultimately lead to the initiation of myelin synthesis.
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Molecular biogeochemistry of modern and ancient marine microbes
… Experimental study of the oxygen requirements of steroid biosynthesis suggests that sterane biomarkers in late Archean rocks are consistent with the persistence of microaerobic surface ocean environments long before the initial oxygenation of the atmosphere. In the second part, using …
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Molecular Biogeochemistry of modern and ancient marine microbes
… Experimental study of the oxygen requirements of steroid biosynthesis suggests that sterane biomarkers in late Archean rocks are consistent with the persistence of microaerobic surface ocean environments long before the initial oxygenation of the atmosphere. In the second part, using …
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The oocyte-to-embryo transition : regulation of oocyte maturation and egg activation in Drosophila
… and transport, the ubiquitination pathway, steroid biosynthesis and metabolism, and a gap junction protein. Additional characterization of these proteins may provide further insight into the regulation of Drosophila maturation and activation.
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Genexpressionsanalysen zur Charakterisierung primärer Mammatumoren im neoadjuvanten Setting
… tumours. On a functional level the expression of steroid hormone and growth factor pathways was identified as a significant difference between the analysed tumours. Both pathways are closely related and affect tumour progression and therapy response in breast cancer. Furthermore, the determined …
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The role of JAK1 and JAK3 in CD8<sup>+</sup> effector T cells
… downregulation of proteins involved in ribosome biosynthesis, steroid biosynthesis, regulation of transcription and the cell cycle; and the upregulation of proteins with hydrolase activity, and with roles in the lysosome and extracellular exosomes. The phosphoproteomic and proteomic data …
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Endocrine aspects of the genetics of mating behavior in the domestic fowl
… reduction of tetrazolium by Δ5,3β hydroxysteroid dehydrogenase was employed to identify the sites of steroid biosynthesis in developing embryos of all three lines. The histochemical procedure proved insufficiently precise for determining the onset of steroidontogenesis or for quantifying …
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Implications For the Role of the Peroxoferric Intermediate In the Second Step of Nitric Oxide Synthase Derived From the Reactivity of P450-Cam With Camphor-5-Oxime and Characterization of the Heme Iron Coordination Structures of Tyrosine- and Histidine-Ligated Heme Enzymes Using Magnetic Circular Dichroism Spectroscopy
… monooxygenases that play critical roles in steroid biosynthesis and drug metabolism. Although discovered over fifty years ago, a major remaining challenge in the study of these enzymes has been to establish the reactivity of the different active oxygen intermediates in the P450 catalytic …
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Search for molecular and metabolic mechanisms contributing to impaired β-cell function
… increased expression of genes in the pathways of steroid biosynthesis, cell cycle, fatty acid metabolism, DNA replication, and biosynthesis of unsaturated fatty acids. Histone-modifying enzyme activity and histone modifications on the genes Insig1, Lss, Peci, Idi1, Hmgcs1 and Casr were found to be …
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Longitudinal gene networks, canonical pathways and functional analysis of microarray data from Longissimus thoracis et lumborum muscle samples of early-weaned Angus steers
… glucuronate interconversions, Sulfur Metabolism, Steroid biosynthesis and PPAR Signaling Pathway were the most recurrent KEGG significant pathways for this microarray analysis. KEGG pathway results were in accordance with the metabolic processes that were expected to happen during the growing and …
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Wirkung von Etomidat auf zelluläre Regulationsmechanismen der Nebennierenrinde
… wurde der Einfluss von Etomidat auf die adrenale Steroidbiosynthese, die ACTH-Rezeptor-Expression und das Proliferationsverhalten der Nebennierenrinde untersucht. Etomidat erwies sich als bislang potentestes Adrenostatikum, das eine frühzeitige Inhibition von P450c11 und in höheren Konzentrationen …
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Studies of aldosterone renin ratio and genetic variation at the CYP11B1/CYP11B2 locus in human essential hypertension
… Alterations in the rate and pattern of adrenal steroid biosynthesis can contribute to blood pressure changes and its heritable component. In humans, mutations in the genes encoding aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1), responsible for the final stages of aldosterone and …