Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"steric stabilization"”.
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In-situ steric stabilization of ultrafine titania particles synthesized by a sol-gel process
… polymeric stabilizers which imparted in-situ steric stability during the particle growth. An attempt was made to elucidate the factors which govern the particle size and morphology by studying the solvent-polymer-particle surface interactions. For this purpose, the effects of polymer …
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Adsorption of Novel Block Copolymers for Steric Stabilization and Flocculation of Colloidal Particles in Aqueous Environments
… solution. The effect of adsorbed polymer on the steric stabilization of alumina particles was studied using sedimentation and electrophoretic mobility experiments. These results do not show conclusively that the triblock copolymer adsorption led to particle stabilization. It is possible that …
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Design Of Functional Dendrimer Nanocarriers And Their Formulations In Propellant-Based Inhalers For Pulmonary Drug Delivery
… is to design biocompatible moieties for the steric stabilization of suspension formulations in HFO-based propellants. Using a combination of tools including ab initio calculation, molecular dynamics simulation and high pressure tensiometry, potential fluorocarbon-philic moieties were …
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Nanostructured gene and drug delivery systems based on molecular self-assembly
… for DNA binding, endosomal escape, steric stabilization, and tissue targeting. This part of the thesis concludes with applications of these systems to two areas of clinical interest: DNA vaccination and tumor targeted gene therapy.
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Preparation of Fully Miscible Nanocomposites
… exchange to be an efficient method to control steric stabilization and compatibilization of nanoparticles. A rational design of polymer binding groups and ligand exchange conditions allows to attach polymer brushes with grafting densities >1 nm^-2 to inorganic nanoparticles for nearly any …
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Multifunctional bioreducible nanoparticles for gene therapy
… have been explored with the goal of improving steric stability and achieving CD44-selective uptake and transfection. Our results show that higher molecular weight HA is required for steric stabilization of the polyplexes while lower molecular weight HA was beneficial for targeted transfection …
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Design, Synthesis, and Characterization of Magnetite Clusters using a Multi Inlet Vortex Mixer
… containing poly (ethylene oxide) to provide steric stabilization and control of size distributions using flash nanoprecipitation. First, the mixer was tested using β-carotene as a model compound to form nanoparticles stabilized with an amphiphilic triblock copolymer poly(propylene …
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Geležies dalelių sintezė vandens ir alyvos terpėse ir jų taikymas tribosistemose /
… with Fe particles, produced Fe particles stabilization and size distribution of obtained particles are described in colloidal chemistry terms: by electrochemical aspects of NaBH4 and LiBEt3H, used surfactants steric stabilization factor. The transmetallization of Fe by copper was …
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Steric and electrosteric stabilization of colloids in aqueous salt solutions
Steric stabilization of colloidal particles occurs through the presence of a layer of adsorbed polymer, and can be important in a number of activities such as paint formulation, treatment of waste water, and drug delivery. Conventional wisdom dictates that the polymer must be attached well, have …
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Statistical mechanical theory of equilibrium structure and miscibility of polymer nanocomposites: effects of polymer chemical heterogeneity and architecture, and nanoparticle surface corrugation and softness
… of corrugation/softness can also result in destabilization by excluding the polymer from its interior. Another route of developing new nanocomposites is by tuning the polymer-particle interfacial chemistry. Prior work has established three states of spatial organization, namely depletion, …
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Solution and Adsorption Characterization of Novel Water-Soluble Ionic Block Copolymers for Stabilization of Magnetite Nanoparticles
… established. Through the analogy of micelles to sterically stabilized nanoparticles, this model was applied to water-soluble block copolymers adsorbed on magnetite nanoparticles for the purpose of tailoring a steric stabilizing brush layer. The sizes of the magnetite-polymer complexes were …
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Nano-Modification for High Performance Cement Composites with Cellulose NanoCrystals and Carbon Nanotubes
… mechanisms are confirmed for the increased DOH: steric stabilization and a new theory referred as short circuit diffusion (SCD), which is more dominant. SCD increases DOH by increasing the transport of water from the pores to the unhydrated cement core through the high density CSH shell. This …
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Sub-micron Patterning of ZnO-PMMA Hybrid Films
… The effects of Van der Waals forces, steric stabilization, depletion flocculation, as well as the physical impediment of entangled polymer chains were considered. A similar agglomeration behavior was shown in the simulations compared to the physical experiments. This thesis shows that …
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Synthesis of Functionalized Poly(dimethylsiloxane)s and the Preparation of Magnetite Nanoparticle Complexes and Dispersions
… successful except for the hydrosilation of the sterically-hindered DIPCS-functionalized PDMS where no reaction was observed. Hydroxyalkyl-terminated PDMS oligomers were successful in initiating the stannous octoate-catalyzed copolymerization of e-caprolactone, which afforded PDMS-b-PCL diblock …
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Studies of adsorption and stabilization of silica suspensions using well-defined polymeric dispersants
… using static light scattering (SLS). The steric stabilization effect of silica dispersions in chlorobenzene by PEOX-PDMS was measured by dynamic light scattering (DLS). The stability was qualitatively related to the average particle hydrodynamic diameter against time. The adsorbed amount …
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Glassy viscoelasticity of dense suspensions of soft colloids and structure & miscibility of soft filler polymer nanocomposites
… PRISM studies of smooth HS filler PNCs. The steric stabilization regime is not sensitive to surface fluctuation magnitude, while the contact clustering and strong bridging regimes are very sensitive to surface fluctuation magnitude. Surface fluctuation smears out surface corrugation and …
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Batch and continuous production of stable dense suspensions of drug nanoparticles in a wet stirred media mill
… during nanoparticle formation and physical stabilization of the nanosuspension with the use of polymers and surfactants (formulation parameters), understanding the impact of process parameters in the context of first-principle-based models, and production of truly nanosized drug particles …
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Poly(2-alkyl-2-oxazoline) containing multiphase systems
… for studying the parameters important for steric stabilization of inorganic particles in polar media. A less defined series of materials was also prepared. Using poly(butyl vinyl ether-co-chloroethyl vinyl ether) random copolymers as: macroinitiators, 2-methyl-2-oxazoline was polymerized, …
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The Design of Stable, Well-Defined Polymer-Magnetite Nanoparticle Systems for Biomedical Applications
… loading and molecular weight necessary to sterically stabilize primary magnetite particles. Anchoring of polyethers to the magnetite nanoparticle surface was examined using three different types of anchor groups: carboxylic acid, ammonium, and zwitterionic phosphonate. As assessed by …
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Development and Evaluation of Brain Tumor Targeted Liposome Delivery System for Paclitaxel
… increased circulation longevity, attributed to steric stabilization effects of PEG, enhanced target accumulation. Near infrared fluorescence imaging demonstrated that these liposomes accumulated selectively in flank tumors with tumor targeting index of 10.59 ± 1.08. Paclitaxel incorporated into …