Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 81 for “"stem cell transplantation"”.
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Saliva and oral mucositis after hematopoietic stem cell transplantation
Contains fulltext : 225513.pdf (Publisher’s version ) (Open Access)
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Mucosal Barrier Injury, Innate Immunity, and Stem Cell Transplantation
Contains fulltext : 87189.pdf (Publisher’s version ) (Open Access)
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Donor lymphocyte infusion after allogeneic stem cell transplantation in children
… syndrome following allogeneic hematopoietic stem cell transplantation (allo HSCT). However, DLI is limited by the development of graft-versus-host disease (GVHD)and marrow aplasia, and the efficacy of DLIis not defined in children. So we evaluate DLI for last decade, and …
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Patients' experience before, during and after stem cell transplantation-phenomenological study
… potentially life threatening treatment such as stem cell transplantation (SCT). The purpose of this study was to develop our understanding of the meaning SCT has for African-American, Latino, and Caucasian patients before, during, and after stem cell treatment. An extensive review of the …
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Improving Leukocyte Recovery Through Physiologically Relevant Oxygen Expansion after Hematopoietic Stem Cell Transplantation
Rapid recovery of lymphocytes post hematopoietic stem cell transplantation (HCT) is correlated with positive patient outcome in treatments of hematologic disease. Few effective clinical therapies exist to enhance lymphocyte recovery, indicating a clear unmet need. Ex vivo expansion of umbilical …
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Cellular and Circuit Level Responses to Neural Stem Cell Transplantation in the Rodent Cortex
Neural stem cell (NSC) transplantation is a promising strategy for the treatment of neurological disease and injury. NSC transplants have been documented to exert both neurotrophic and immunomodulatory effects in pathological contexts, but grafted cells frequently remain undifferentiated. The …
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Analysis of Therapeutic Effect after Human Mesenchymal Stem Cell Transplantation in Ischemic Stroke Rat
Background and PURPOSE: Mesenchymal stem cells (MSCs) have recently been investigated as an attractive therapeutic tool for ischemic stroke because of their plasticity and availability. For the understanding of therapeutic effect of MSCs after transplantation in ischemic rats, changes in free fatty …
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Immunotolerance regeneration by T regulatory cells in autologous haematopoietic stem cell transplantation for multiple sclerosis
… an autoimmune disease of the central nervous system (CNS). Autologous haematopoietic stem cell transplantation (AHSCT) has received increasing attention in recent years as a therapeutic option for treatment refractory MS. AHSCT has been proposed to induce long-term remission by initiating an …
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Tumor immune escape in allogeneic stem cell transplantation: Releasing the brake on graft-versus-tumor immunity
Contains fulltext : 101020.pdf (Publisher’s version ) (Open Access)
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Exploring Prevalence and Management of Anxiety in Children and Adolescents with Cancer or Undergoing Hematopoietic Stem Cell Transplantation
… with cancer or undergoing hematopoietic stem cell transplantation (HSCT), to estimate the burden of anxiety and to describe guideline recommendations for assessing and managing anxiety in this population. The three papers comprising this dissertation established several key findings, …
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Hematopoietic Stem Cell Threshold Sensing Controls Regulatory Pathways Facilitating Clinically Relevant Ex Vivo Expansion for Stem Cell Transplantation
<p>The ex vivo expansion of hematopoietic stem cells (HSCs) for transplantation has threefold importance: 1.) First, because of the rarity of stem cells there often isn’t a sufficient supply obtainable from common sources for larger children and adults. 2.) Secondly, patient morbidity and time to …
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Role of the Tcell genotype in the development of allogeneic responses after stem cell transplantation and cellular immunotherapy.
Contains fulltext : 19390.pdf (Publisher’s version ) (Open Access)
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UNVEILING HUMAN NATURAL KILLER CELLS ONTOGENESIS IN HOMEOSTATIC CONDITIONS AND DURING THE IMMUNE RECONSTITUTION AFTER HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION
Natural Killer (NK) cells are potent members of the innate immune system, as they are endowed with the capacity of sensing and eliminating tumor-transformed and viral infected cells by integrating a plethora of inhibitory and activating signals coming from a repertoire of germline encoded receptors …
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Treatment Outcomes in Children with Very High Risk Acute Lymphoblastic Leukemia Intended to Treat with Allogeneic Hematopoietic Stem Cell Transplantation
… chemotherapy. Recently, allogeneic hematopoietic stem cell transplantation (Allo-HSCT) was use to treat the patients with VHR ALL. We studied the clinical course and outcomes of children with VHR ALL intended treat with Allo-HSCT after chemotherapy. 16 children who were diagnosed as VHR ALL and …
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Role of Lymphocyte Populations Following Allogeneic Haematopoietic Stem Cell Transplantation // Роля на лимфоцитните популации след алогенна трансплантация на хемопоетични стволови клетки
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is an established therapeutic approach for a range of malignant and benign haematological disorders. Despite significant advances in the field of transplantation medicine, this method remains associated with a number of complications – …
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Stimulation of donor t-cells with leukemic blast-loaded dendritic cells for the generation of leukemia-specific immunity in the context of allogeneic stem cell transplantation
… with chemotherapy and in some cases also by stem cell transplantation (SCT). The relapse rates are high, and long-term disease-free survival occurs in less than half of the AML patients. The curative potential of the allogeneic SCT can be explained by the pre-transplant chemo/radiotherapy in …
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"It really kind of like cuts my existence into two": an interpretative phenomenological analysis of the experience of adults with sickle cell disease receiving curative Haematopoietic Stem Cell Transplantation (HSCT)
Background: Sickle cell disease (SCD) is the most common single gene disorder in England. At present, Haematopoietic Stem Cell Transplantation (HSCT) is the only cure, and as of 2020, these have been funded for adults with SCD by the National Health Service (NHS) in England. Rationale: The …
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Ice Recrystallization Inhibition as a Mechanism for Reducing Cryopreservation Injury in a Hematopoietic Stem Cell Model
… technical applications, such as hematopoeitic stem cell transplantation and sperm banking, sometimes require the use of cryopreserved cells. Cryopreservation, however, can induce cell injury and reduce the yields of viable functional cells. Ice recrystallization is a mechanism of …
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