Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"stem cell homing"”.
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Human Mesenchymal Stem Cell Homing to Glioma Stem Cell Xenografts
… and the microsatellite populations of tumor cells scattered throughout the brain parenchyma. However, bone marrow-derived human mesenchymal stem cells (hMSCs) offer a viable alternative to enhance therapeutic delivery – one that overcomes current limitations. hMSCs are a population of cells …
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Homing and Differentiation of Mesenchymal Stem Cells in 3D In Vitro Models
Mesenchymal stem cells (MSCs) have great potential to improve clinical outcomes for many inflammatory and degenerative diseases through delivery of exogenous MSCs via injection or cell-laden scaffolds and through mobilization and migration of endogenous MSCs to injury sites. MSC fate and function …
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Affinity Flow Fractionation for label-free cell sorting
Capture and isolation of flowing cells from body fluids such as peripheral blood, bone marrow or pleural effusion has enormous implications in diagnosis, disease monitoring, and drug testing. However, in many situations the conventional methods of cell sorting are of limited use due to complex …
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STUDIES OF CELL MOTILITY AND DIFFERENTIATION IN COMPLEX 3D IN VITRO MICROENVIRONMENT
<p>Cell behaviors, such as motility and differentiation, which are highly regulated by the complex 3D in vivo microenvironment, have been extensively studied in the past decades to better understand the mechanisms of development, disease, and healing. Due to the highly complex nature of the in vivo …
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Molecular Mechanisms Regulating Chemokine Receptor CXCR4 Signaling and Trafficking
… (GPCR) that binds to the chemokine, stromal cell-derived factor-1 (SDF-1alpha; a.k.a. CXCL12). The SDF-1alpha/CXCR4 signaling axis plays an essential role during embryogenesis in the development of the heart, brain and vasculature and in the adult mediating immune cell trafficking and stem …