Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"stem cell fate regulation"”.
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Translational mechanisms of stem cell fate regulation in epidermal oncogene tolerance
… we find that oncogenic RAS-induced progenitor cell hyperproliferation is coordinated with differentiation to restrain aberrant growth and preserve epidermal development. We uncover a novel translation mechanism mediated by initiation factor eIF2B5 that co-regulates RAS proliferation and …
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Multigradient hydrogels to decode extrinsic regulation of hematopoietic stem cell fate
… for the generation of all the blood and immune cells of the body. The cells responsible for this process are the hematopoietic stem cells (HSCs), primarily located within the bone marrow. They are housed in specific microenvironments (niches) that provide stochastically and temporally mutable …