Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"statistical alignment"”.
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Identification of evolutionarily conserved nucleic acid secondary structures within viral genomes
… of HIV-1 and seven flavivirus species revealed statistically significant associations between base-paired nucleotide positions and various patterns of mutation. While the results of the various analyses carried out were consistent with the presence of between one and five highly-conserved …
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Statistical analysis of short template switch mutations in human genomes
… and deletions. In this thesis, I describe statistical methods for the detection and interpretation of short template switch mutations within DNA sequence data. I then use my methods to explore small-scale template switch mutagenesis within human genome evolution, population variation, and …